Abstract:Aim To explore the influential factors of slow flow following rotational atherectomy (RA) and the predictive value of these factors. Methods According to the presence or absence of slow flow (defined as transient thrombolysis in myocardial infarction (TIMI) flow grade ≤2 just after RA), a total of 219 cases undergoing RA were divided into slow flow group (n=50) and non-slow flow group (n=169). The clinical history, laboratory examinations, and coronary intervention data of the two groups were compared. The two-class Logistic regression model was used to analyze independent influential factors of slow flow, the operating characteristic (ROC) curve was used to evaluate the predictive value. Results There were 50 patients (22.8%) in the slow flow group. Compared with the non-slow flow group, the final burr size of 1.25 mm was more used in the slow flow group (P＜0.05), while the final burr size of 1.5 mm was fewer (P＜0.05); Lesion length and total run time were longer, rotation times were higher (P＜0.05); while systolic blood pressure was lower in the slow flow group, and reference diameter was significantly smaller (P＜0.05). The two-class Logistic regression analysis showed that lesion length was an independent risk factor for slow flow, while reference diameter and systolic blood pressure were preventive factors (P＜0.05). Combined use of these variables provided incremental predictive value for slow flow after RA procedure, and the area under the curve was 0.736 with 78.0% sensitivity and 65.1% specificity. Conclusion Lesion length was an independent risk factor of slow flow, while reference diameter and systolic blood pressure were preventive factors, and the combination of these variables provided additional predictive value for slow flow in patients undergoing RA.

Abstract:Aim To study the detection of carotid artery intima plaque in elderly hospitalized patients with hypertension and its influencing factors. Methods A total of 328 elderly hypertensive patients were selected,and color Doppler ultrasound was used to detect all patients carotid artery intima plaque and grading.Patients sex,age,the course of hyperpiesia,the controls of high blood pressure in the past,the smoking history,family history of hypertension,history of stroke and other messages were noted by clinical records. Results The detection rate of carotid artery intima plaque was 77.4%,in which class 1,class 2 and 3 accounted for 32.0%,36.9% and 8.5%(plague score).Ordered Logistic regression univariate cumulative analysis showed that male,old,poorly controlled blood pressure,longer duration of hypertension were risk factors for plaque.Multivariate analysis showed that the major risk factors for plaque were male,old age and poor control of blood pressure. Conclusion Hypertension in the elderly patients with higher rate of carotid artery intima plaque,and male patients,old age,patients whose blood pressure was in poor control were the high-risk groups.