Abstract:Chylomicrons, as the main source of intestinal triglyceride-rich lipoproteins and their remnants, can promote the occurrence and development of atherosclerosis. Therefore, reducing chylomicrons and their remnants are expected to be one of the effective methods to reduce the residual risk of cardiovascular disease. This review describes the key proteins in the production of chylomicrons and their molecular mechanisms, as well as the progress of Chinese and Western medicine therapy systematically in order to provide reliable new ideas for the prevention and treatment of atherosclerosis.

Abstract:A long-standing association exists between elevated triglyceride levels and coronary heart disease(CHD).However,the extent to which triglycerides directly promote CHD or represent an independent factor of risk has been debated for decades. This paper aims to review the latest advances in the relationship between triglycerides and coronary heart disease from the aspects of pathophysiology and epidemiology,so as to clarify the role triglycerides play in atherogenicity and CHD.