2020, 28(7):610-615.
Abstract:Aim Tissue Doppler imaging (TDI) and two-dimensional speckle tracking imaging (2D-STI) were used to evaluate the changes of left atrial pressure and function and their relationship with left ventricular function in patients with coronary heart disease (CHD) before and after percutaneous coronary intervention (PCI), so as to provide more effective information for clinical treatment of CHD. Methods Maximal left atrial volume (LAVmax), minimal left atrial volume (LAVmin), pre-atrial contraction left atrial volume (LAVpre), left atrial passive emptying fraction (LAPEF), left atrial active emptying fraction (LAAEF), left ventricular ejection fraction (LVEF), early velocity of mitral valve (E), atrial contractile velocity of mitral valve (A) were measured and calculated by echocardiography before PCI, 1 week after PCI and 3 months after PCI in 30 CHD patients. Early diastole velocity of mitral valve annulus (e’), left atrial mean pressure (mLAP), E/A and E/e’ were measured and calculated by TDI. Left ventricular systolic global longitudinal strain (GLS), mean systolic peak strain rate (mSRs), mean early diastolic peak strain rate (mSRe), mean late diastolic peak strain rate (mSRa) were measured and calculated by 2D-STI. Another 30 cases with coronary artery stenosis rate less than 30% measured by coronary angiography were selected as the control group. Results Compared with the control group, LVEF, LAPEF, E, E/A, e’, mSRs, mSRe and GLS decreased, A, E/e’, mLAP, LAVmin, LAVmax, LAVpre, LAAEF and mSRa increased at different time in the CHD group (P<0.05). In the CHD group, there were no significant difference in all the indexes between 1 week after PCI and before PCI (P>0.05); Compared with before PCI and 1 week after PCI, E, e’, E/A, mSRs, mSRe, GLS, LVEF and LAPEF increased, while A, E/e’, mLAP, LAVmin, LAVmax, LAVpre, LAAEF and mSRa decreased at 3 months after PCI (P<0.05). At 3 months after PCI in the CHD group, mLAP was positively correlated with GLS, mSRe, LAVmin, LAVmax and LAVpre (r=0.8,0.1,0.1,0.8,0.857, P<0.01), and negatively correlated with LVEF, E/A, mSRa, mSRs and LAPEF (r=-0.800, -0.884, -0.898, -0.829, -0.427, P<0.05). Conclusions The function of left atrium and left ventricle in CHD patients is improved significantly in 3 months after PCI compared with that in 1 week after PCI and before PCI. The changes of left atrial pressure and function can comprehensively reflect the changes of left atrial and left ventricular function in CHD patients after PCI, which are closely related to each other.
2010, 18(4):311-314.
Abstract:Aim To evaluate the left ventricular functions of acute organophosphate poisoning patient(AOPP)using mitral annular motion velocities measured by Doppler tissue imaging (DTI). Methods Tissue Doppler velocity mode was used to observe mitral annulus movement in 78 cases with AOPP and 32 healthy adults. After mitral annular pulsed-wave rate of E/A were measured by traditional echocardiographic,the peak value of mitral annular early diastolic velocity (Em),late diastolic velocity(Am)were analyzed by DTI. Results E/A>Em/Am>1 was observd in health control group as well as the mild-moderate AOPP; Em/AmP><0.001). Conclusion The left ventricle function,in terms of contraction and relaxation,was decreased in the cases with severe AOPP compared with health control group and mild-moderate group. TDI is a useful tool to assess left ventricle function in the cases with AOPP.
2009, 17(11):947-949.
Abstract:Aim To explore the value of tissue doppler imaging in the evaluation of ventricular function in patients with end-stage renal disease. Methods 31 patients with end-stage renal disease of the normal eject factionand 31 healthy subjects were selected for routine 2D and tissue doppler imaging.Left ventricular eject faction,interventricular septum thickness,left ventricular posterior wall thickness,left ventricular internal dimensions and left ventricular internal dimensions were measured.Conventional left and right ventricular diastolic function parameters were acquired by pulsed doppler.Including to the mitral and tricuspid flow velocity,the ratio of the mitral and tricuspid early diastolic velocity and late diastolic velocity were calculated.The mitral and tricuspid annular early and late diastolic velocities were determined by tissue doppler imaging in apical views(4-and 2-chamber),and the ratio of the mitral and tricuspid early diastolic velocity and the mitral and tricuspid annular early diastolic velocities,and the ratio of the mitral and tricuspid annular early diastolic velocities and late diastolic velocities were calculated.Then function parameters of the end-stage renal disease group were compared with healthy group,and the corrections between the parameters were analyzed. Results The end-stage renal disease patients had lower ratio of the mitral and tricuspid early diastolic velocity and late diastolic velocity,the mean mitrial and tricuspid systolic velocities,the mean mitral and tricuspid annular early and late diastolic velocities,the mean ratio of the mitral and tricuspid annular early diastolic velocities and late diastolic velocities were significantly reduced,while the ratio of the mitral and tricuspid early diastolic velocity and the mitral and tricuspid annular early diastolic velocities was significantly increased. Conclusion Patients with end-stage renal disease had left and right ventriculars diastolic dysfunction,and so were systolic function.Systolic was impaired in patients with end-stage renal disease with normal ejection fraction.