Calcified nodule and acute coronary syndrome
Author:
Affiliation:

1.Jinan Institute of Cardiovascular Diseases & Department of Cardiology, the Fourth People's Hospital of Jinan,Jinan, Shandong 250031, China;2.Department of Cardiac Catheterization Laboratory, the Fourth People's Hospital of Jinan, Jinan, Shandong 250031, China;3.Department of Emergency, the Fourth People's Hospital of Jinan, Jinan, Shandong 250031, China)

Clc Number:

R541.4

  • Article
  • | |
  • Metrics
  • |
  • Reference [32]
  • | | | |
  • Comments
    Abstract:

    Atherosclerotic calcified nodule is rare but important cause of coronary artery thrombosis and acute coronary syndrome. Eruptive calcified nodule is characterized by clusters of burst like calcified fragments protruding into the lumen accompanied by ruptured fibrous caps and thrombus attached to the surface, which is a potential cause of sudden cardiac death. The prognosis of acute coronary syndrome caused by calcified nodule is poor, and the incidence of perioperative myocardial infarction, cardiac death, and target lesion revascularization is high. This article reviews the progress in the diagnosis and treatment of atherosclerotic calcified nodule in coronary artery.

    Reference
    [1] SUGANE H, KATAOKA Y, OTSUKA F, et al.Cardiac outcomes in patients with acute coronary syndrome attributable to calcified nodule.Atherosclerosis, 1,8:70-75.
    [2] YAHAGI K, DAVIS H R, ARBUSTINI E, et al.Sex differences in coronary artery disease:pathological observations.Atherosclerosis, 5,9(1):260-267.
    [3] LEE J B, MINTZ G S, LISAUSKAS J B, et al.Histopathologic validation of the intravascular ultrasound diagnosis of calcified coronary artery nodules.Am J Cardiol, 1,8(11):1547-1551.
    [4] XU Y J, MINTZ G S, TAM A, et al.Prevalence, distribution, predictors, and outcomes of patients with calcified nodules in native coronary arteries:a 3-vessel intravascular ultrasound analysis from Providing Regional Observations to Study Predictors of Events in the Coronary Tree (PROSPECT).Circulation, 2,6(5):537-545.
    [5] LEE T, MINTZ G S, MATSUMURA M, et al.Prevalence, predictors, and clinical presentation of a calcified nodule as assessed by optical coherence tomography.JACC Cardiovasc Imaging, 7,0(8):883-891.
    [6] SATO T, MATSUMURA M, YAMAMOTO K, et al.Impact of eruptive vs noneruptive calcified nodule morphology on acute and long-term outcomes after stenting.JACC Cardiovasc Interv, 3,6(9):1024-1035.
    [7] SUGIYAMA T, YAMAMOTO E, FRACASSI F, et al.Calcified plaques in patients with acute coronary syndromes.JACC Cardiovasc Interv, 9,2(6):531-540.
    [8] JIA H B, ABTAHIAN F, AGUIRRE A D, et al.In vivo diagnosis of plaque erosion and calcified nodule in patients with acute coronary syndrome by intravascular optical coherence tomography.J Am Coll Cardiol, 3,2(19):1748-1758.
    [9] SAKAMOTO A, VIRMANI R, FINN A V, et al.Calcified nodule as the cause of acute coronary syndrome:connecting bench observations to the bedside.Cardiology, 8,9(2):101-104.
    [10] YAHAGI K, KOLODGIE F D, OTSUKA F, et al.Pathophysiology of native coronary, vein graft, and in-stent atherosclerosis.Nat Rev Cardiol, 6,3(2):79-98.
    [11] NAKAJIMA A, ARAKI M, KURIHARA O, et al.Comparison of post-stent optical coherence tomography findings among three subtypes of calcified culprit plaques in patients with acute coronary syndrome.Catheter Cardiovasc Interv, 1,7(4):634-645.
    [12] GUAGLIUMI G, PELLEGRINI D, MAEHARA A, et al.All calcified nodules are made equal and require the same approach:pros and cons.EuroIntervention, 3,9(2):e110-e112.
    [13] 程增为, 胡司淦.富含Gla蛋白参与冠状动脉钙化机制的研究进展.中国动脉硬化杂志, 3,1(1):88-92.CHENG Z W, HU S G.Research progress on the mechanism of Gla-rich protein involvement in coronary ar-tery calcification.Chin J Arterioscler, 3,1(1):88-92.
    [14] VIRMANI R, BURKE A P, FARB A, et al.Pathology of the vulnerable plaque.J Am Coll Cardiol, 6,7(8 Suppl):C13-C18.
    [15] TERADA K, KUBO T, KAMEYAMA T, et al.NIRS-IVUS for differentiating coronary plaque rupture, erosion, and calcified nodule in acute myocardial infarction.JACC Cardiovasc Imaging, 1,4(7):1440-1450.
    [16] LIU Y F, MA Y H, WANG C Y, et al.A comparison of computed tomography imaging with histopathology in the sensitivity and correlation of evaluating coronary arterial calcification.Quant Imaging Med Surg, 3,3(4):2426-2440.
    [17] LI J, LI J, JIAN Z J, et al.Serum marker and CT characteristics of coronary calcified nodule assessed by intravascular ultrasound.BMC Cardiovasc Disord, 2,2(1):475.
    [18] MOTOYAMA S, KONDO T, SARAI M, et al.Multislice computed tomographic characteristics of coronary lesions in acute coronary syndromes.J Am Coll Cardiol, 7,0(4):319-326.
    [19] NOGAMI K, SUGIYAMA T, HOSHINO M, et al.Progression from nodular calcification to calcified nodules leading to acute myocardial infarction.CJC Open, 3,5(6):490-492.
    [20] DEMUYAKOR A, HU S N, KONIAEVA E, et al.Impact of nodular calcification in patients with acute coronary syndrome (ACS) treated with primary percutaneous coronary intervention (PCI).BMC Cardiovasc Disord, 2,2(1):103.
    [21] WATANABE Y, SAKAKURA K, TANIGUCHI Y, et al.Comparison of clinical outcomes of intravascular ultrasound-calcified nodule between percutaneous coronary intervention with versus without rotational atherectomy in a propensity-score matched analysis.PLoS One, 0,5(11):e0241836.
    [22] JINNOUCHI H, SAKAKURA K, TANIGUCHI Y, et al.Clinical outcomes and unique restenosis of calcified nodule in heavily calcified coronary artery.J Atheroscler Thromb, 3,0(6):649-662.
    [23] MOROFUJI T, KURAMITSU S, SHINOZAKI T, et al.Clinical impact of calcified nodule in patients with heavily calcified lesions requiring rotational atherectomy.Catheter Cardiovasc Interv, 1,7(1):10-19.
    [24] KOBAYASHI N, TAKANO M, TSURUMI M, et al.Features and outcomes of patients with calcified nodules at culprit lesions of acute coronary syndrome:an optical coherence tomography study.Cardiology, 8,9(2):90-100.
    [25] BLACHUTZIK F, HONTON B, ESCANED J, et al.Safety and effectiveness of coronary intravascular lithotripsy in eccentric calcified coronary lesions:a patient-level pooled analysis from the disrupt CAD I and CAD II studies.Clin Res Cardiol, 1,0(2):228-236.
    [26] MATSUDA Y, ASHIKAGA T, SASAOKA T, et al.Ostial left circumflex lesion with calcified nodule successfully treated with excimer laser coronary atherectomy and drug-coated balloon.J Cardiol Cases, 0,2(1):32-35.
    [27] YOSHIHIRO I, ATSUSHI F, TOMOKO K, et al.Debulking of coronary-artery calcified nodule observed by optical frequency domain imaging and angioscopy.Coron Artery Dis, 1,2(7):671-672.
    [28] ISHIDA M, ISHISONE T, KIMURA T, et al.Stent-less percutaneous coronary intervention of calcified nodule causing non-ST-elevation myocardial infarction-serial optical coherence tomography follow-up after rotational atherectomy followed by drug-coated balloon angioplasty.Circ J, 2,6(2):336.
    [29] SATO Y, FINN A V, VIRMANI R.Calcified nodule:a rare but important cause of acute coronary syndrome with worse clinical outcomes.Atherosclerosis, 1,8:40-42.
    [30] GRINES C L, TUMMALA P E.Calcified coronary nodule:tip of the iceberg on a road full of thorns.Catheter Cardiovasc Interv, 3,1(5):959-960.
    [31] PRATI F, GATTO L, FABBIOCCHI F, et al.Clinical outcomes of calcified nodules detected by optical coherence tomography:a sub-analysis of the CLIMA study.EuroIntervention, 0,6(5):380-386.
    [32] NAKANO H, KATAOKA Y, OTSUKA F, et al.Refractory in-stent restenosis attributable to eruptive calcified nodule.JACC Case Rep, 0,2(12):1872-1878.
    Related
    Cited by
    Comments
    Comments
    分享到微博
    Submit
Get Citation

LIU Qiang, YANG Xiaohan, DU Qing. Calcified nodule and acute coronary syndrome[J]. Editorial Office of Chinese Journal of Arteriosclerosis,2024,32(7):641-644.

Copy
Share
Article Metrics
  • Abstract:168
  • PDF: 2912
  • HTML: 0
  • Cited by: 0
History
  • Received:August 23,2023
  • Revised:November 19,2023
  • Online: July 05,2024
Article QR Code