Mitochondria-associated organelle crosstalk in myocardial ischemia/reperfusion injury

doi:10.20039/j.cnki.10073949.2024.06.004.

Home > Archive>Volume 32, Issue 6, 2024 >481-486. DOI:10.20039/j.cnki.10073949.2024.06.004.

Mitochondria-associated organelle crosstalk in myocardial ischemia/reperfusion injury
DOI:
                        10.20039/j.cnki.10073949.2024.06.004.
                    
CSTR:
                        
                    
Author:
                        YAO Hui1YAO Hui
Institute of Cardiovascular Disease, University of South China & Key Laboratory for Arteriosclerology of Hunan Province & Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease,
Find this author on All Journals
Find this author on BaiDu
Search for this author on this site
XIE Yuxin1,2XIE Yuxin
Institute of Cardiovascular Disease, University of South China & Key Laboratory for Arteriosclerology of Hunan Province & Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, ;Department of Pharmacology, School of Pharmacy, University of South China, Hengyang, Hunan 421001, China
Find this author on All Journals
Find this author on BaiDu
Search for this author on this site
LI Chaoquan1LI Chaoquan
Institute of Cardiovascular Disease, University of South China & Key Laboratory for Arteriosclerology of Hunan Province & Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease,
Find this author on All Journals
Find this author on BaiDu
Search for this author on this site
LIU Wanting1,2LIU Wanting
Institute of Cardiovascular Disease, University of South China & Key Laboratory for Arteriosclerology of Hunan Province & Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, ;Department of Pharmacology, School of Pharmacy, University of South China, Hengyang, Hunan 421001, China
Find this author on All Journals
Find this author on BaiDu
Search for this author on this site
LUO Yaqian1LUO Yaqian
Institute of Cardiovascular Disease, University of South China & Key Laboratory for Arteriosclerology of Hunan Province & Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease,
Find this author on All Journals
Find this author on BaiDu
Search for this author on this site
YI Guanghui1,2YI Guanghui
Institute of Cardiovascular Disease, University of South China & Key Laboratory for Arteriosclerology of Hunan Province & Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, ;Department of Pharmacology, School of Pharmacy, University of South China, Hengyang, Hunan 421001, China
Find this author on All Journals
Find this author on BaiDu
Search for this author on this site

                    
Affiliation:1.Institute of Cardiovascular Disease, University of South China & Key Laboratory for Arteriosclerology of Hunan Province & Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, ;2.Department of Pharmacology, School of Pharmacy, University of South China, Hengyang, Hunan 421001, China)
Clc Number:R5;R363
Fund Project:

Article

Figures

Metrics

Reference

Cited by

Materials

Comments

Abstract:

Damage to organelles plays a significant role in myocardial ischemia/reperfusion injury, which results in the dysfunction of mitochondria and other related organelles. The communication between mitochondria and other organelles can also affect the development of myocardial ischemia/reperfusion injury. For instance, the mitochondria-associated endoplasmic reticulum membrane provides a “seamless connection” and regulates the exchange of organelles and metabolites (such as ions, lipids and proteins) between the mitochondria and the endoplasmic reticulum, which subsequently affects myocardial ischemia/reperfusion injury. However, there is a lack of studies regarding the interaction between mitochondria and related organelles, which is a critical component in triggering myocardial ischemia/reperfusion injury. Therefore, this article describes the role of mitochondrial crosstalk with endoplasmic reticulum, lysosomes and nuclei in myocardial ischemia/reperfusion injury, and aims to provide a theoretical basis for targeting mitochondrial crosstalk with other organelles in the treatment of myocardial ischemia/reperfusion injury.

Key words:mitochondria; organelle crosstalk; myocardial ischemia/reperfusion injury; mitochondria-associated endoplasmic reticulum membrane; lysosomes; cell nucleus

Get Citation

YAO Hui, XIE Yuxin, LI Chaoquan, LIU Wanting, LUO Yaqian, YI Guanghui. Mitochondria-associated organelle crosstalk in myocardial ischemia/reperfusion injury[J]. Editorial Office of Chinese Journal of Arteriosclerosis,2024,32(6):481-486.

Copy

Article Metrics

Abstract:
PDF:
HTML:
Cited by:

History

Received:January 12,2024
Revised:May 06,2024
Adopted:
Online: July 04,2024
Published:

Policies & Instructions

Get Citation

Share

Article Metrics

History

Article QR Code