2025年5月23日 周五
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Research progress of T-cadherin in coronary heart disease
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1.College of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;2.Hunan University of Chinese Medicine & Hunan Provincial Key Laboratory of TCM Diagnositics, Changsha, Hunan 410208, China;3.Traditional Chinese Medicine Hospital of Sangzhi County, Zhangjiajie, Hunan 427000, China)

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R5

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    Abstract:

    T-cadherin (T-cad) is a newly discovered adiponectin receptor, which can bind to adiponectin hexamer and high molecular weight polymer. T-cad is widely expressed in many tissues in vivo, especially in the cardiovascular system. T-cad is closely related to coronary heart disease, and has the effects of inhibiting cell apoptosis, preventing atherosclerosis, limiting vascular intimal hyperplasia, inducing vascular endothelial cell proliferation, promoting the secretion of growth factors, and promoting muscle regeneration. Therefore, exploring the mechanism of T-cad in coronary heart disease may provide new ideas for the diagnosis and treatment of coronary heart disease.

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ZHAO Yanzhen, JIAN Weixiong, ZHONG Yin. Research progress of T-cadherin in coronary heart disease[J]. Editorial Office of Chinese Journal of Arteriosclerosis,2024,32(1):87-92.

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History
  • Received:March 25,2023
  • Revised:May 07,2023
  • Online: February 05,2024
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