Programmed cell death related pathways regulate vascular calcification
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Central Laboratory, Fuxing Hospital, Capital Medical University, Beijing 100038, China)

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R5

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    Abstract:

    Vascular calcification is age dependent and a risk factor for cardiovascular all-cause mortality. Recently, growing evidences have shown that novel forms of programmed cell death including ferroptosis, pyroptosis, and autophagy play an important role in the development of vascular calcification. This review introduces the molecular mechanism of programmed cell death and its relationship with vascular calcification, elucidates the evidence of anti-vascular calcification by regulating the cell death pathway key molecules.

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YANG Yang, YAO Zhichao, HUO Lirong. Programmed cell death related pathways regulate vascular calcification[J]. Editorial Office of Chinese Journal of Arteriosclerosis,2023,31(12):1098-1104.

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History
  • Received:March 09,2023
  • Revised:April 22,2023
  • Online: December 29,2023
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