Dyslipidemia is a human metabolic disease caused by a variety of complex causes, traditional Chinese medicine crataegi folium, gynostemma pentaphyllum, alismatis rhizoma, polygoni cuspidati rhizoma et radix, and ginkgo folium have therapeutic effects on dyslipidemia. This article reviews the effects of the common traditional Chinese medicine crataegi folium, gynostemma pentaphyllum, alismatis rhizoma, polygoni cuspidati rhizoma et radix, ginkgo folium in the treatment of dyslipidemia, and suggests that these traditional Chinese medicine may have some potential advantages in the prevention and treatment of dyslipidemia-related diseases such as atherosclerosis.