Research progress in the relationship between Akkermansia and atherosclerosis
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1.Department of Cardiology, the 2nd Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, China;2.The Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, Heilongjiang 150001, China;3.Department of Cardiology, the 1st Affiliated Hospital of University of South China, Hengyang, Hunan 421001, China)

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R5

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    Abstract:

    Atherosclerosis (As), a complex chronic inflammatory disease, that is a major cause of cardiovascular diseases (CVD) including ischemic heart disease and stroke, causing high morbidity and mortality worldwide. In recent years, the role of gut microbiota in atherosclerosis has received extensive attention. However, as an important anti-atherosclerosis beneficial bacteria, Akkermansia is rarely reviewed. In-depth study of the pathogenesis and potential treatment of atherosclerosis is the focus of current medical development. Therefore, this article reviews how Akkermansia exerts its anti-atherosclerotic effect and its relationship with anti-atherosclerotic drugs.

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ZHAO Peng, ZHENG Yuqi, TIAN Jinwei, LIU Xinxin. Research progress in the relationship between Akkermansia and atherosclerosis[J]. Editorial Office of Chinese Journal of Arteriosclerosis,2023,31(5):456-460.

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History
  • Received:August 31,2022
  • Revised:October 29,2022
  • Online: May 19,2023
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