Research progress in the relationship between Akkermansia and atherosclerosis

doi:10.20039/j.cnki.1007 3949.2023.05.013

Home > Archive>Volume 31, Issue 5, 2023 >456-460. DOI:10.20039/j.cnki.1007 3949.2023.05.013

Research progress in the relationship between Akkermansia and atherosclerosis
DOI:
                        10.20039/j.cnki.1007 3949.2023.05.013
                    
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                        ZHAO Peng1,2ZHAO Peng
Department of Cardiology, the 2nd Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, China;The Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, Heilongjiang 150001, China
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ZHENG Yuqi3ZHENG Yuqi
Department of Cardiology, the 1st Affiliated Hospital of University of South China, Hengyang, Hunan 421001, China
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TIAN Jinwei1,2TIAN Jinwei
Department of Cardiology, the 2nd Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, China;The Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, Heilongjiang 150001, China
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LIU Xinxin1,2LIU Xinxin
Department of Cardiology, the 2nd Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, China;The Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, Heilongjiang 150001, China
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Affiliation:1.Department of Cardiology, the 2nd Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, China;2.The Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, Heilongjiang 150001, China;3.Department of Cardiology, the 1st Affiliated Hospital of University of South China, Hengyang, Hunan 421001, China)
Clc Number:R5
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Abstract:

Atherosclerosis (As), a complex chronic inflammatory disease, that is a major cause of cardiovascular diseases (CVD) including ischemic heart disease and stroke, causing high morbidity and mortality worldwide. In recent years, the role of gut microbiota in atherosclerosis has received extensive attention. However, as an important anti-atherosclerosis beneficial bacteria, Akkermansia is rarely reviewed. In-depth study of the pathogenesis and potential treatment of atherosclerosis is the focus of current medical development. Therefore, this article reviews how Akkermansia exerts its anti-atherosclerotic effect and its relationship with anti-atherosclerotic drugs.

Key words:atherosclerosis; Akkermansia; berberine; statin; metformin

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ZHAO Peng, ZHENG Yuqi, TIAN Jinwei, LIU Xinxin. Research progress in the relationship between Akkermansia and atherosclerosis[J]. Editorial Office of Chinese Journal of Arteriosclerosis,2023,31(5):456-460.

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Received:August 31,2022
Revised:October 29,2022
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Online: May 19,2023
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