Research progress on the application of biomimetic nanocarriers functionalized with erythrocyte membrane for atherosclerosis therapy

doi:10.20039/j.cnki.10073949.2023.01.001

Home > Archive>Volume 31, Issue 1, 2023 >1-8. DOI:10.20039/j.cnki.10073949.2023.01.001

Research progress on the application of biomimetic nanocarriers functionalized with erythrocyte membrane for atherosclerosis therapy
DOI:
                        10.20039/j.cnki.10073949.2023.01.001
                    
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                        CAO YuCAO Yu
Key Laboratory for Biorheological Science and Technology of Ministry of Education ＆ State and Local Joint Engineering Laboratory for Vascular Implants ＆ Bioengineering College of Chongqing University, Chongqing 400030, China
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MOU NianlianMOU Nianlian
Key Laboratory for Biorheological Science and Technology of Ministry of Education ＆ State and Local Joint Engineering Laboratory for Vascular Implants ＆ Bioengineering College of Chongqing University, Chongqing 400030, China
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ZHU LiZHU Li
Key Laboratory for Biorheological Science and Technology of Ministry of Education ＆ State and Local Joint Engineering Laboratory for Vascular Implants ＆ Bioengineering College of Chongqing University, Chongqing 400030, China
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WANG YiWANG Yi
Key Laboratory for Biorheological Science and Technology of Ministry of Education ＆ State and Local Joint Engineering Laboratory for Vascular Implants ＆ Bioengineering College of Chongqing University, Chongqing 400030, China
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WANG GuixueWANG Guixue
Key Laboratory for Biorheological Science and Technology of Ministry of Education ＆ State and Local Joint Engineering Laboratory for Vascular Implants ＆ Bioengineering College of Chongqing University, Chongqing 400030, China
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WU WeiWU Wei
Key Laboratory for Biorheological Science and Technology of Ministry of Education ＆ State and Local Joint Engineering Laboratory for Vascular Implants ＆ Bioengineering College of Chongqing University, Chongqing 400030, China
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Affiliation:Key Laboratory for Biorheological Science and Technology of Ministry of Education ＆ State and Local Joint Engineering Laboratory for Vascular Implants ＆ Bioengineering College of Chongqing University, Chongqing 400030, China)
Clc Number:R363；R5
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Abstract:

In recent years, the use of cell membrane-coated nanoparticles to develop biomimetic nanomedicines for atherosclerosis treatment has become a research hotspot. Among various cell membranes, due to the unique biological properties, red blood cells have been widely used as drug delivery. Erythrocyte membrane camouflaged biomimetic nanomedicines can not only prolong the circulation time and improve the biocompatibility in vivo, but also exhibit excellent passive targets through the enhanced permeability and retention effects of lesions for safe and efficient atherosclerosis therapy.Herein, this paper reviews erythrocyte membrane coating technology in the application of constructing the biomimetic nanomediciens in recent years, and focuses on its research applications in atherosclerosis therapy.

Key words:erythrocyte membrane; nano; biomimetic; drug carrier; atherosclerosis

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CAO Yu, MOU Nianlian, ZHU Li, WANG Yi, WANG Guixue, WU Wei. Research progress on the application of biomimetic nanocarriers functionalized with erythrocyte membrane for atherosclerosis therapy[J]. Editorial Office of Chinese Journal of Arteriosclerosis,2023,31(1):1-8.

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Received:February 11,2022
Revised:May 06,2022
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Online: December 26,2022
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