2025年5月25日 周日
Home > Archive>Volume 30, Issue 9, 2022 >787-792. DOI:10.20039/j.cnki.1007-3949.2022.09.007
PDF HTML XML Export Cite reminder
Correlation analysis between CT-FFR and coronary stenosis based on artificial intelligence
Author:
Affiliation:

Department of Medical Imaging Center, the Affiliated Hospital of Qinghai University, Xining, Qinghai 810001, China)

Clc Number:

R5

  • Article
    • | |
  • Metrics
    • |
  • Reference [18]
    • |
  • Related
    • |
  • Cited by
    • | |
  • Comments
    Abstract:

    Aim To investigate the correlation between coronary artery stenosis, calcification score and coronary hemodynamics in patients with coronary heart disease based on the CT-fractional flow reserve (CT-FFR) of artificial intelligence. Methods The clinical and coronary CT angiography (CCTA) datas of 206 patients with suspected coronary heart disease in the Affiliated Hospital of Qinghai University from September 2020 to April 2021 were included in this study retrospectively. The CT-FFR, coronary artery calcification score and stenosis degree of coronary artery were analyzed by artificial intelligence software, including left anterior descending artery, left circumflex branch and right coronary artery. The patients were divided into two groups according to the CT-FFR value. The vessels with CT-FFR≤0.8 were divided into functional meaning group, and the rest are non-functional meaning group. The correlations between coronary artery stenosis and calcification score and coronary hemodynamics were analyzed. Results 365 blood vessels from 206 patients were included in the study,and there were 139 blood vessels in the functional meaning group and 226 blood vessels in the non-functional meaning group. Degree of coronary stenosis (r＝－0.473, P＜0.001) and calcification score (r＝－0.369, P＜0.001) were negatively correlated with CT-FFR, and the calcification score was weakly correlated with the degree of stenosis (r＝0.141,P＝0.007). Compared with non-functional meaning group, the age of onset was older, and the proportion of male patients, hypertension, smoking history were significantly higher than those in the non-functional meaning group. Conclusion Degree of coronary stenosis and calcification score are important factors affecting coronary hemodynamics, CT-FFR is helpful for the functional evaluation of CCTA in coronary artery disease.

    Reference
    [1] 中国心血管健康与疾病报告编写组.中国心血管健康与疾病报告2020概要.中国循环杂志, 1,6(6):521-545.THE WRITING COMMITTEE OF THE REPORT ON CARDIOVASCULAR HEALTH AND DISEASES IN CHINA.Report on cardiovascular health and diseases burden in China:an updated summary of 2020.Chin Circ J, 1,6(6):521-545.
    [2] DEWEY M, SIEBES M, KACHELRIE M, et al.Quantitative cardiac imaging study group.clinical quantitative cardiac imaging for the assessment of myocardial ischaemia.Nat Rev Cardiol, 0,7(7):427-450.
    [3] 徐磊, 张龙江, 张佳胤, 等.无创性CT血流储备分数研究现状与展望.中华放射学杂志, 0,4(10):921-924.XU L, ZHANG L J, ZHANG J Y, et al.Fractional flow reserve derived from CT:current status and future direction.Chin J Radiol, 0,4(10):921-924.
    [4] NRGAARD B L, TERKELSEN C J, MATHIASSEN O N, et al.Coronary CT angiographic and flow reserve-guided management of patients with stable ischemic heart disease.J Am Coll Cardiol, 8,2(18):2123-2134.
    [5] NRGAARD B L, LEIPSIC J, GAUR S, et al.Diagnostic performance of noninvasive fractional flow reserve derived from coronary computed tomography angiography in suspected coronary artery disease:the NXT trial(analysis of coronary blood flow using CT angiography:next steps).J Am Coll Cardiol, 4,3(12):1145-1155.
    [6] AHMADI A, KINI A, NARULA J.Discordance between ischemia and stenosis, or PINSS and NIPSS:are we ready for new vocabulary.JACC Cardiovasc Imaging, 5,8(1):111-114.
    [7] 周慧源, 赵狄, 董平栓.冠心病临界病变患者血糖水平与冠脉血流储备分数的相关性研究.中国循证心血管医学杂志, 1,3(1):74-77.ZHOU H Y, ZHAO D, DONG P S.Correlation between blood glucose level and fractional flow reserve in patients with coronary intermediate lesion.Chin J Evid Based Cardiovasc Med, 1,3(1):74-77.
    [8] 王晓泉, 张佳胤, 李跃华.冠状动脉钙化积分评价冠状动脉弹性的研究.实用放射学杂志, 6,2(1):80-82.WANG XQ, ZHANG J Y, LI Y H.A study of the applyment of the coronary calcium score to evaluate the coronary distensibility.J Pract Radiol, 6,2(1):80-82.
    [9] YUONESS S A, GOHA A M, ROMSA J G, et al.Very high coronary artery calcium score with normal myocardial perfusion SPECT imaging is associated with a moderate incidence of severe coronary artery disease.Eur J Nucl Med Mol Imaging, 5,2(10):1542-1550.
    [10] ASSANTE R, ZAMPELLA E, ARUMUGAM P, et al.Quantitative relationship between coronary artery calcium and myocardial blood flow by hybrid rubidium-82 PET/CT imaging in patients with suspected coronary artery disease.J Nucl Cardiol, 7,4(2):494-501.
    [11] NRGAARD B L, MORTENSEN M B, PARNER E, et al.Clinical outcomes following real-world computed tomography angiography-derived fractional flow reserve testing in chronic coronary syndrome patients with calcification.Eur Heart J Cardiovasc Imaging, 1,2(10):1182-1189.
    [12] VIRMANI R, BURKE A P, KOLODGIE F D, et al.Vulnerable plaque:the pathology of unstable coronary lesions.J Interv Cardiol, 2,5(6):439-446.
    [13] 李永霞, 马跃虎, 王同兴, 等.基于CCTA对胸痛病人高危斑块成分及血流动力学特征的研究.国际医学放射学杂志, 1,4(1):19-24.LI Y X, MA Y H, WANG T X, et al.Plaque and hemodynamic characteristics of cardiac artery on coronary CT angiography in patients with highrisk plaque and chest pain.Int J Med Radiol, 1,4(1):19-24.
    [14] 郭明秋, 殷晓捷, 刁殿琰, 等.脂质代谢水平与冠状动脉粥样硬化病变的关系.中国动脉硬化杂志, 1,9(2):149-155.GUO M Q, YIN X J, DIAO D Y, et al.Relationship between the levels of lipid metabolism and coronary atherosclerotic lesions.Chin J Arterioscler, 1,9(2):149-155.
    [15] RALLIDIS L S, PITSAVOS C, PANAGIOTAKOS D B, et al.Non-high density lipoprotein cholesterol is the best discriminator of myocardial infarction in young individuals.Atherosclerosis, 5,9(2):305-309.
    [16] TAYLOR C A, FONTE T A, MIN J K.Computational fluid dynamics applied to cardiac computed tomography for noninvasive quantification of fractional flow reserve:scientific basis.J Am Coll Cardiol, 3,1(22):2233-2241.
    [17] AHMADI N, RUIZ-GARCIA J, HAJSADEGHI F, et al.Impaired coronary artery distensibility is an endothelium-dependent process and is associated with vulnerable plaque composition.Clin Physiol Funct Imaging, 6,6(4):261-268.
    [18] PIJLS N H, FEARON W F, TONINO P A, et al.Fractional flow reserve versus angiography for guiding percutaneous coronary intervention in patients with multivessel coronary artery disease:2-year follow-up of the FAME (Fractional Flow Reserve Versus Angiography for Multivessel Evaluation) study.J Am Coll Cardiol, 0,6(3):177-184.
    Related
    Cited by
Get Citation

WEI Jia, BAO Haihua, WANG Xueyan, BAI Xin. Correlation analysis between CT-FFR and coronary stenosis based on artificial intelligence[J]. Editorial Office of Chinese Journal of Arteriosclerosis,2022,30(9):787-792.

Copy
Share
Article Metrics
  • Abstract:
  • PDF:
  • HTML:
  • Cited by:
History
  • Received:December 06,2021
  • Revised:February 24,2022
  • Online: July 30,2022
Article QR Code

You are the 48936 visitor

Post Code：421001 Fax：0734-8160523

Phone：0734-8160765 E-mail：dmzzbjb@163.net

Editorial Office of Chinese Journal of Arteriosclerosis ® 2025