The progress of the national preclinical research of atherosclerosis in the recent three years

doi:10.20039/j.cnki.1007-3949.2022.09.002

Home > Archive>Volume 30, Issue 9, 2022 >744-752. DOI:10.20039/j.cnki.1007-3949.2022.09.002

The progress of the national preclinical research of atherosclerosis in the recent three years
DOI:
                        10.20039/j.cnki.1007-3949.2022.09.002
                    
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                        ZHI ChenxiZHI Chenxi
Clinical Anatomy & Reproductive Medicine Application Institute, Hengyang Medical School, University of South China, Hengyang, Hunan 421001, China
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XIE ZhongchengXIE Zhongcheng
Clinical Anatomy & Reproductive Medicine Application Institute, Hengyang Medical School, University of South China, Hengyang, Hunan 421001, China
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LI LiangLI Liang
Clinical Anatomy & Reproductive Medicine Application Institute, Hengyang Medical School, University of South China, Hengyang, Hunan 421001, China
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PENG TianhongPENG Tianhong
Clinical Anatomy & Reproductive Medicine Application Institute, Hengyang Medical School, University of South China, Hengyang, Hunan 421001, China
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XIE WeiXIE Wei
Clinical Anatomy & Reproductive Medicine Application Institute, Hengyang Medical School, University of South China, Hengyang, Hunan 421001, China
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Affiliation:Clinical Anatomy & Reproductive Medicine Application Institute, Hengyang Medical School, University of South China, Hengyang, Hunan 421001, China)
Clc Number:R5
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Abstract:

Atherosclerosis (As) is a pathological process which is tightly related to cardiovascular diseases. Because of its high risks to human health, Chinese scholars have carried out a large number of researches in recent 3 years, which focus on the model and the pathogenesis and risk factors of As, such as ferroptosis, pyroptosis, autophagy, gut microflora, exosomes, oxidative stress, low shear stress, non-coding RNA. Intensive and in-depth preclinical researches provide novel ideas for the selection of prevention and treatment strategies and drug research of As, in order to achieve clinical transformation. This paper reviews the preclinical researches on As conducted by Chinese scholars in recent 3 years.

Key words:atherosclerosis; programmed death; gut microbiota; low shear stress; non-coding RNA

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ZHI Chenxi, XIE Zhongcheng, LI Liang, PENG Tianhong, XIE Wei. The progress of the national preclinical research of atherosclerosis in the recent three years[J]. Editorial Office of Chinese Journal of Arteriosclerosis,2022,30(9):744-752.

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Received:January 21,2022
Revised:April 20,2022
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Online: July 30,2022
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