Research progress of asialoglycoprotein receptor 1 in atherosclerosis

Home > Archive>Volume 30, Issue 6, 2022 >541-545

Research progress of asialoglycoprotein receptor 1 in atherosclerosis
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                        XIA MengdieXIA Mengdie
Institute of Cardiovascular Disease, University of South China & Key Laboratory for Arteriosclerology of Hunan Province & Human International Scientific and Technological Cooperation Base of Arteriosclerotic Disease & Hengyang Medical College, University of South China, Hengyang, Hunan 421001, China
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LIAO WeiLIAO Wei
Institute of Cardiovascular Disease, University of South China & Key Laboratory for Arteriosclerology of Hunan Province & Human International Scientific and Technological Cooperation Base of Arteriosclerotic Disease & Hengyang Medical College, University of South China, Hengyang, Hunan 421001, China
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XIANG QiongXIANG Qiong
Institute of Cardiovascular Disease, University of South China & Key Laboratory for Arteriosclerology of Hunan Province & Human International Scientific and Technological Cooperation Base of Arteriosclerotic Disease & Hengyang Medical College, University of South China, Hengyang, Hunan 421001, China
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CUI YutingCUI Yuting
Institute of Cardiovascular Disease, University of South China & Key Laboratory for Arteriosclerology of Hunan Province & Human International Scientific and Technological Cooperation Base of Arteriosclerotic Disease & Hengyang Medical College, University of South China, Hengyang, Hunan 421001, China
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ZHOU YatingZHOU Yating
Institute of Cardiovascular Disease, University of South China & Key Laboratory for Arteriosclerology of Hunan Province & Human International Scientific and Technological Cooperation Base of Arteriosclerotic Disease & Hengyang Medical College, University of South China, Hengyang, Hunan 421001, China
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GAN NiGAN Ni
Institute of Cardiovascular Disease, University of South China & Key Laboratory for Arteriosclerology of Hunan Province & Human International Scientific and Technological Cooperation Base of Arteriosclerotic Disease & Hengyang Medical College, University of South China, Hengyang, Hunan 421001, China
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TANG ZhihanTANG Zhihan
Institute of Cardiovascular Disease, University of South China & Key Laboratory for Arteriosclerology of Hunan Province & Human International Scientific and Technological Cooperation Base of Arteriosclerotic Disease & Hengyang Medical College, University of South China, Hengyang, Hunan 421001, China
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Affiliation:Institute of Cardiovascular Disease, University of South China & Key Laboratory for Arteriosclerology of Hunan Province & Human International Scientific and Technological Cooperation Base of Arteriosclerotic Disease & Hengyang Medical College, University of South China, Hengyang, Hunan 421001, China)
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Abstract:

Atherosclerosis is the main pathological basis of cardiovascular disease, which is a serious threat to human health all over the world. Atherosclerosis is a chronic inflammatory process of vascular wall caused by lipid metabolism disorder. As a member of the lectin family, the asialoglycoprotein receptor 1 is involved in endocytosis and degradation of serum glycoproteins, and plays an important role in various physiological processes. Studies have shown that the asialoglycoprotein receptor 1 mutations are associated with cardiovascular disease risk such as low density lipoprotein cholesterol levels, suggesting that asialoglycoprotein receptor 1 may be closely associated with the development and progression of atherosclerosis. This article reviews the role of the asialoglycoprotein receptor 1 in atherosclerosis and its possible mechanisms.

Key words:asialoglycoprotein receptor 1; atherosclerosis; lipid metabolism; cardiovascular disease

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XIA Mengdie, LIAO Wei, XIANG Qiong, CUI Yuting, ZHOU Yating, GAN Ni, TANG Zhihan. Research progress of asialoglycoprotein receptor 1 in atherosclerosis[J]. Editorial Office of Chinese Journal of Arteriosclerosis,2022,30(6):541-545.

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Received:February 25,2022
Revised:April 04,2022
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Online: May 10,2022
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