2025年5月24日 周六
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Research progress of succinate and atherosclerosis
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Affiliation:

1.Department of Cardiovascular Medicine, The Second Affiliated Hospital, University of South China, Hengyang, Hunan 421001, China;2.Institute of Cardiovascular Diseases, Hengyang Medical School, University of South China, Hengyang, Hunan 421001,China)

Clc Number:

R5

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    Abstract:

    Cardiovascular disease is the leading cause of death. Moreover, the incidence of cardiovascular disease in young/middle-aged people (18~45 years old) is still on the rise. Early diagnosis, early warning and treatment of cardiovascular disease are important topics in the current medical research field. Atherosclerosis is the pathophysiological basis of many cardiovascular diseases. Recent studies have shown that the tricarboxylic acid (TCA) cycle intermediate is involved in the occurrence and development of atherosclerosis, and considered as the early diagnosis and warning bio-markers for atherosclerosis. Here, the roles and underlying mechanisms of succinate in the initiation and progression in atherosclerosis were reviewed.

    Reference
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ZENG Yan, WEI Dangheng, ZENG Gaofeng. Research progress of succinate and atherosclerosis[J]. Editorial Office of Chinese Journal of Arteriosclerosis,2022,30(1):83-87.

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History
  • Received:September 26,2021
  • Revised:November 28,2021
  • Online: January 07,2022
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