Research progress of adipose dysfunction involved in the regulation of cardiovascular homeostasis imbalance

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Research progress of adipose dysfunction involved in the regulation of cardiovascular homeostasis imbalance
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                        SHI XiaodongSHI Xiaodong
Department of Physiology and Pathophysiology, College of Basic Medicine, Fudan University, Shanghai 200032, China
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RUAN ChengchaoRUAN Chengchao
Department of Physiology and Pathophysiology, College of Basic Medicine, Fudan University, Shanghai 200032, China
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Affiliation:Department of Physiology and Pathophysiology, College of Basic Medicine, Fudan University, Shanghai 200032, China)
Clc Number:R33;R5
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Abstract:

With the changes of living standard and lifestyle, metabolic cardiovascular diseases characterized by obesity are increasing by years. The disorder of adipose function and adipocytokines, because of adipose tissue’s pathological expansion induced by obesity, participates in the whole process of the occurrence and development of cardiovascular disease. This article reviews different types of adipose tissue involve in maintenance of cardiovascular homeostasis or regulation of cardiovascular disease by endocrine or paracrine effects under physiological or pathological conditions. Therefore, it provides new ideas and new targets for the precise treatment of obesity-related metabolic cardiovascular diseases.

Key words:obesity; adipose tissue; cardiovascular disease; endocrine; paracrine

Reference

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SHI Xiaodong, RUAN Chengchao. Research progress of adipose dysfunction involved in the regulation of cardiovascular homeostasis imbalance[J]. Editorial Office of Chinese Journal of Arteriosclerosis,2022,30(1):21-26.

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Received:August 04,2021
Revised:October 26,2021
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Online: January 07,2022
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