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Application of nano-drug delivery for treatment of myocardial infarction and its complications
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1.Deparment of Cardiovascular Medicine, the 2nd Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, China;2.College of Pharmacy, Harbin Medical University, Harbin, Heilongjiang 150081, China;3.The Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, Heilongjiang 150001, China;4.Translational Medicine Research and Cooperation Center of Northern China, Heilongjiang Academy of Medical Sciences, Harbin, Heilongjiang 150081, China)

Clc Number:

R542.2

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    Abstract:

    Myocardial infarction (MI) and its concomitant malignant arrhythmia, pathological ventricular remodeling and other complications are seriously harmful to human health. At present, drug therapy is the main strategy to stabilize plaque and reduce myocardial ischemia-reperfusion injury. Recent studies have shown that nano-drug delivery has great potential to benefit targeted therapy and enhance the safety and efficacy of drug treatment. This paper summarizes the present development of nano-drug delivery, and reviews the prospects of the treatment of myocardial infarction and its complications.

    Reference
    [1] LIBBY P, RIDKER P M, HANSSON G K.Progress and challenges in translating the biology of atherosclerosis.Nature, 1,3(7347):317-325.
    [2] 田进伟, 符亚红.动脉粥样硬化易损斑块快速进展机制与临床治疗进展.中国动脉硬化杂志, 9,7(4):277-280.
    [3] 李雪.急性心肌梗死后缺血再灌注性心律失常发病机制及预防的研究.世界最新医学信息文摘, 9,9(83):114-115.
    [4] FORSYTH P, MOIR L, SPEIRITS I, et al.Improving medication optimisation in left ventricular systolic dysfunction after acute myocardial infarction.BMJ Open Qual, 9,8(3):e000676.
    [5] KHAFAJI M, ZAMANI M, GOLIZADEH M, et al.Inorganic nanomaterials for chemo/photothermal therapy:a promising horizon on effective cancer treatment.Biophys Rev, 9,1(3):335-352.
    [6] CUTRONE G, QIU J, MENENDEZ-MIRANDA M, et al.Comb-like dextran copolymers:a versatile strategy to coat highly porous MOF nanoparticles with a PEG shell.Carbohydr Polym, 9,3:115085.
    [7] KROLL A V, FANG R H, ZHANG L.Biointerfacing and applications of cell membrane-coated nanoparticles.Bioconjug Chem, 7,8(1):23-32.
    [8] SONG Y, HUANG Z, LIU X, et al.Platelet membrane-coated nanoparticle-mediated targeting delivery of Rapamycin blocks atherosclerotic plaque development and stabilizes plaque in apolipoprotein E-deficient (ApoE－/－) mice.Nanomedicine, 9,5(1):13-24.
    [9] WANG Y, ZHANG K, QIN X, et al.Biomimetic nanotherapies:red blood cell based Core-Shell structured nanocomplexes for atherosclerosis management.Adv Sci (Weinh), 9,6(12):1900172.
    [10] CHIANI M, SHOKRGOZAR M A, AZADMANESH K, et al.Preparation, characterization, and in vitro evaluation of bleomycin-containing nanoliposomes.Chem Biol Drug Des, 7,9(4):492-497.
    [11] LOBATTO M E, FAYAD Z A, SILVERA S, et al.Multimodal clinical imaging to longitudinally assess a nanomedical anti-inflammatory treatment in experimental atherosclerosis.Mol Pharm, 0,7(6):2020-2029.
    [12] GOTHWAL A, KHAN I, GUPTA U.Polymeric micelles:recent advancements in the delivery of anticancer drugs.Pharm Res, 6,3(1):18-39.
    [13] PETERS D, KASTANTIN M, KOTAMRAJU V R, et al.Targeting atherosclerosis by using modular, multifunctional micelles.Proc Natl Acad Sci U S A, 9,6(24):9815-9819.
    [14] KATSUKI S, MATOBA T, NAKASHIRO S, et al.Nanoparticle-mediated delivery of pitavastatin inhibits atherosclerotic plaque destabilization/rupture in mice by regulating the recruitment of inflammatory monocytes.Circulation, 4,9(8):896-906.
    [15] SHARMA H, MISHRA P K, TALEGAONKAR S, et al.Metal nanoparticles:a theranostic nanotool against cancer.Drug Discov Today, 5,0(9):1143-1151.
    [16] DOBROVOLSKAIA M A, PATRI A K, SIMAK J, et al.Nanoparticle size and surface charge determine effects of PAMAM dendrimers on human platelets in vitro.Mol Pharm, 2,9(3):382-393.
    [17] HOLME M N, FEDOTENKO I A, ABEGG D, et al.Shear-stress sensitive lenticular vesicles for targeted drug delivery.Nat Nanotechnol, 2,7(8):536-543.
    [18] DVIR T, BAUER M, SCHROEDER A, et al.Nanoparticles targeting the infarcted heart.Nano Lett, 1,1(10):4411-4414.
    [19] KORNMUELLER K, VIDAKOVIC I, PRASSL R.Artificial high density lipoprotein nanoparticles in cardiovascular research.Molecules, 9,4(15):2829.
    [20] JIANG C, QI Z, HE W, et al.Dynamically enhancing plaque targeting via a positive feedback loop using multifunctional biomimetic nanoparticles for plaque regression.J Control Release, 9,8:71-85.
    [21] WANG Y, LI L, ZHAO W, et al.Targeted therapy of atherosclerosis by a Broad-Spectrum reactive Oxygen species scavenging nanoparticle with intrinsic anti-inflammatory activity.ACS Nano, 8,2(9):8943-8960.
    [22] ARYAL S, PARK H, LEARY J F, et al.Top-down fabrication-based nano/microparticles for molecular imaging and drug delivery.Int J Nanomedicine, 9,4:6631-6644.
    [23] LI X, WANG C, TAN H, et al.Gold nanoparticles-based SPECT/CT imaging probe targeting for vulnerable atherosclerosis plaques.Biomaterials, 6,8:71-80.
    [24] CHAPON C, FRANCONI F, LEMAIRE L, et al.High field magnetic resonance imaging evaluation of superparamagnetic iron oxide nanoparticles in a permanent rat myocardial infarction.Invest Radiol, 3,8(3):141-146.
    [25] LIPINSKI M J, ALBELDA M T, FRIAS J C, et al.Multimodality imaging demonstrates trafficking of liposomes preferentially to ischemic myocardium.Cardiovasc Revasc Med, 6,7(2):106-112.
    [26] SOSNOVIK D E, NAHRENDORF M, DELIOLANIS N, et al.Fluorescence tomography and magnetic resonance imaging of myocardial macrophage infiltration in infarcted myocardium in vivo.Circulation, 7,5(11):1384-1391.
    [27] SONG J, YU J, LI Y, et al.Mr targeted imaging for the expression of tenascin-C in myocardial infarction in vivo.J Magn Reson Imaging, 7,5(6):1668-1674.
    [28] OOSTENDORP M, DOUMA K, WAGENAAR A, et al.Molecular magnetic resonance imaging of myocardial angiogenesis after acute myocardial infarction.Circulation, 0,1(6):775-783.
    [29] KAMALY N, FREDMAN G, FOJAS J J, et al.Targeted interleukin-10 nanotherapeutics developed with a microfluidic chip enhance resolution of inflammation in advanced atherosclerosis.ACS Nano, 6,0(5):5280-5292.
    [30] NAKASHIRO S, MATOBA T, UMEZU R, et al.Pioglitazone-Incorporated nanoparticles prevent plaque destabilization and rupture by regulating monocyte/macrophage differentiation in ApoE－/－ mice.Arterioscler Thromb Vasc Biol, 6,6(3):491-500.
    [31] LEUSCHNER F, DUTTA P, GORBATOV R, et al.Therapeutic siRNA silencing in inflammatory monocytes in mice.Nat Biotechnol, 1,9(11):1005-1010.
    [32] ICHIMURA K, MATOBA T, NAKANO K, et al.A translational study of a new therapeutic approach for acute myocardial infarction:Nanoparticle-mediated delivery of pitavastatin into reperfused myocardium reduces ischemia-reperfusion injury in a preclinical porcine model.PLoS One, 6,1(9):e0162425.
    [33] YAJIMA S, MIYAGAWA S, FUKUSHIMA S, et al.Prostacyclin analogue-loaded nanoparticles attenuate myocardial ischemia/reperfusion injury in rats.JACC Basic Transl Sci, 9,4(3):318-331.
    [34] SAYED N, TAMBE P, KUMAR P, et al.miRNA transfection via poly(amidoamine)-based delivery vector prevents hypoxia/reperfusion-induced cardiomyocyte apoptosis.Nanomedicine (Lond), 0,5(2):163-181.
    [35] TAKAHAMA H, SHIGEMATSU H, ASAI T, et al.Liposomal amiodarone augments anti-arrhythmic effects and reduces hemodynamic adverse effects in an ischemia/reperfusion rat model.Cardiovasc Drugs Ther, 3,7(2):125-132.
    [36] SOMASUNTHARAM I, BOOPATHY A V, KHAN R S, et al.Delivery of Nox2-NADPH oxidase siRNA with polyketal nanoparticles for improving cardiac function following myocardial infarction.Biomaterials, 3,4(31):7790-7798.
    [37] BEJERANO T, ETZION S, ELYAGON S, et al.Nanoparticle delivery of miRNA-21 mimic to cardiac macrophages improves myocardial remodeling after myocardial infarction.Nano Lett, 8,8(9):5885-5891.
    [38] PERIOLI L, PAGANO C, CECCARINI M R.Current highlights about the safety of inorganic nanomaterials in healthcare.Curr Med Chem, 9,6(12):2147-2165.
    [39] 吴学平, 李志宏, 王新艳, 等.心肌梗死后心脏修复与心肌细胞再生的研究进展.中国动脉硬化杂志, 9,7(10):899-904.
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PIAO Minghui, QU Wenbo, LIU Bing, TIAN Jinwei. Application of nano-drug delivery for treatment of myocardial infarction and its complications[J]. Editorial Office of Chinese Journal of Arteriosclerosis,2021,29(11):989-994.

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History
  • Received:May 19,2020
  • Revised:June 20,2020
  • Online: November 18,2021
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