Research progress of angiogenesis in atherosclerotic plaque
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Hunan University of Chinese Medicine, Changsha, Hunan 410208, China)

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R5

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    Abstract:

    Atherosclerosis is the main cause of cardio-cerebrovascular related diseases. Among the influencing factors of atherosclerosis, angiogenesis is one of the main causes of plaque rupture and various complications. Hypoxia, inflammation and growth factor-related factors can cause angiogenesis in plaques and lead to atherosclerosis. This article reviews the related factors affecting angiogenesis and their mechanism, in order to provide new ideas and intervention targets for the prevention and treatment of atherosclerosis.

    Reference
    [1] 范骎, 陶蓉, 张瑞岩, 等.炎症反应在易损斑块中的作用及其机制研究进展.中国动脉硬化杂志, 9,7(4):301-306.
    [2] AKWII R G, SAJIB M S, ZAHRA F T, et al.Role of angiopoietin-2 in vascular physiology and pathophysiology.Cells, 9,8(5):471.
    [3] BAI Y, BAI L, ZHOU J, et al.Sequential delivery of VEGF, FGF-2 and PDGF from the polymeric system enhance HUVECs angiogenesis in vitro and CAM angiogenesis.Cell Immunol, 8,3:19-32.
    [4] DALTON A C, SHLAMKOVITCH T, PAPO N, et al.Constitutive association of tie1 and tie2 with endothelial integrins is functionally modulated by angiopoietin-1 and fibronectin.PLoS One, 6,1(10):e0163732.
    [5] MUPPALA S, XIAO R, KRUKOVETS I, et al.Thrombospondin-4 mediates TGF-β-induced angiogenesis.Oncogene, 7,6(36):5189-5198.
    [6] SUN C, FENG S B, CAO Z W, et al.Up-regulated expression of matrix metalloproteinases in endothelial cells mediates platelet microvesicle-induced angiogenesis.Cell Physiol Biochem, 7,1(6):2319-2332.
    [7] BLOOR C M.Angiogenesis during exercise and training.Angiogenesis, 5,8(3):263-271.
    [8] ZHANG Y, CLIFF W J, SCHOEFL G I, et al.Immunohistochemical study of intimal microvessels in coronary atherosclerosis.Am J Pathol, 3,3(1):164-172.
    [9] PRENEN H, MAZZONE M.Tumor-associated macrophages:a short compendium.Cell Mol Life Sci, 9,6(8):1447-1458.
    [10] CHISTIAKOV D A, MELNICHENKO A A, MYASOEDOVA V A, et al.Role of lipids and intraplaque hypoxia in the formation of neovascularization in atherosclerosis.Ann Med, 7,9(8):661-677.
    [11] SLUIMER J C, DAEMEN M J.Novel concepts in atherogenesis:angiogenesis and hypoxia in atherosclerosis.J Pathol, 9,8(1):7-29.
    [12] BITTO A, DE C G, POLITO F, et al.Evidence for markers of hypoxia and apoptosis in explanted human carotid atherosclerotic plaques.J Vasc Surg, 0,2(4):1015-1021.
    [13] SHAN F, HUANG Z, XIONG R, et al.HIF1α-induced upregulation of KLF4 promotes migration of human vascular smooth muscle cells under hypoxia.J Cell Physiol, 0,5(1):141-150.
    [14] RUPARELIA N, CHOUDHURY R.Inflammation and atherosclerosis:what is on the horizon?.Heart, 0,6(1):80-85.
    [15] XU S, KAMATO D, LITTLE P J, et al.Targeting epigenetics and non-coding RNAs in atherosclerosis:from mechanisms to therapeutics.Pharmacol Ther, 9,6:15-43.
    [16] PARMA L, BAGANHA F, QUAX P H, et al.Plaque angiogenesis and intraplaque hemorrhage in atherosclerosis.Eur J Pharmacol, 7,6:107-115.
    [17] SLUIMER J C, KOLODGIE F D, BIJNENS A P, et al.Thin-walled microvessels in human coronary atherosclerotic plaques show incomplete endothelial junctions relevance of compromised structural integrity for intraplaque microvascular leakage.J Am Coll Cardiol, 9,3(17):1517-1527.
    [18] SEDDING D G, BOYLE E C, DEMANDT J, et al.Vasa vasorum angiogenesis:key player in the initiation and progression of atherosclerosis and potential target for the treatment of cardiovascular disease.Front Immunol, 8,9:706.
    [19] DEVRIES M R, QUAX P H.Plaque angiogenesis and its relation to inflammation and atherosclerotic plaque destabilization.Curr Opin Lipidol, 6,7(5):499-506.
    [20] GUO M, CAI Y, HE C, et al.Coupled modeling of lipid deposition, inflammatory response and intraplaque angiogenesis in atherosclerotic plaque.Ann Biomed Eng, 9,7(2):439-452.
    [21] LI X, SUN X, CARMELIET P.Hallmarks of endothelial cell metabolism in health and disease.Cell Metab, 9,0(3):414-433.
    [22] CRIVELLATO E.The role of angiogenic growth factors in organogenesis.Int J Dev Biol, 1,5(4/5):365-375.
    [23] KOYAMA N, HART C E, CLOWES A W.Different functions of the platelet-derived growth factor-alpha and -beta receptors for the migration and proliferation of cultured baboon smooth muscle cells.Circ Res, 4,5(4):682-691.
    [24] LEE S H, JEONG D, HAN Y S, et al.Pivotal role of vascular endothelial growth factor pathway in tumor angiogenesis.Ann Surg Treat Res, 5,9(1):1-8.
    [25] SHIBUYA M.Vascular endothelial growth factor and its receptor system:physiological functions in angiogenesis and pathological roles in various diseases.J Biochem, 3,3(1):13-19.
    [26] ZHU H, GAO M, GAO X, et al.Vascular endothelial growth factor-B:impact on physiology and pathology.Cell Adh Migr, 8,2(3):215-227.
    [27] ZHANG Y, BAI Y, JING Q, et al.Functions and regeneration of mature cardiac lymphatic vessels in atherosclerosis, myocardial infarction, and heart failure.Lymphat Res Biol, 8,6(6):507-515.
    [28] SHIBUYA M.Vascular endothelial growth factor receptor-2:its unique signaling and specific ligand, VEGF-E.Cancer Sci, 3,4(9):751-756.
    [29] KOCH S, TUGUES S, LI X, et al.Signal transduction by vascular endothelial growth factor receptors.Biochem J, 1,7(2):169-183.
    [30] HIN T J, HAO T D, LIM J J, et al.JAK/STAT signaling in hepatocellular carcinoma.Hepat Oncol, 0,7(1):HEP18.
    [31] HU B, WANG J, WU X, et al.Interleukin-17 upregulates vascular endothelial growth factor by activating the JAK/STAT pathway in nucleus pulposus cells.Joint Bone Spine, 7,4(3):327-334.
    [32] ALBASANZ-PUIG A, MURRAY J, NAMEKATA M, et al.Opposing roles of STAT-1 and STAT-3 in regulating vascular endothelial growth factor expression in vascular smooth muscle cells.Biochem Biophys Res Commun, 2,8(1):179-184.
    [33] THURSTON G, KITAJEWSKI J.VEGF and Delta-Notch:interacting signalling pathways in tumour angiogenesis.Br J Cancer, 8,9(8):1204-1209.
    [34] FOURNIER P, VIALLARD C, DEJDA A, et al.The protein tyrosine phosphatase PTPRJ/DEP-1 contributes to the regulation of the Notch-signaling pathway and sprouting angiogenesis.Angiogenesis, 0,3(2):145-157.
    [35] GAO W, SWEENEY C, CONNOLLY M, et al.Notch-1 mediates hypoxia-induced angiogenesis in rheumatoid arthritis.Arthritis Rheum, 2,4(7):2104-2113.
    [36] PHNG L K, GERHARDT H.Angiogenesis:a team effort coordinated by notch.Dev Cell, 9,6(2):196-208.
    [37] ZHOU X L, LIU J C.Role of notch signaling in the mammalian heart.Braz J Med Biol Res, 4,7(1):1-10.
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WANG Yanlei, YAN Xu, LIU Chunhua, YANG Junhui. Research progress of angiogenesis in atherosclerotic plaque[J]. Editorial Office of Chinese Journal of Arteriosclerosis,2021,29(8):732-736.

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History
  • Received:May 29,2020
  • Revised:April 12,2021
  • Online: August 10,2021
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