Severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2) infects host cells through ACE2, CD147 and GRP78 receptors, causing 2019 coronavirus disease (COVID-19), and partially inducing acute myocardial injury and chronic damage to the cardiovascular system. Therefore, special attention should be paid to the protection of the heart during treatment for COVID-19. This issue continues with an expert presentation on SARS- CoV-2 infection and myocardial injury to deepen the understanding of COVID-19 and its cardiovascular injury and improve the prevention and treatment.