As its high morbidity, serious harm, with poor prognosis and high death rate, cardiovascular disease has always been the focus of the world, especially myocardial infarction(MI) with higher mortality, and with increased morbidity year by year, which should be focused on by each patient. Recent years, along with constantly emerging studies of acute infection causing increased risk of myocardial infarction, it attracts the attention of multidisciplinary physicians. This article reviews the progress of acute infection increasing the risk of myocardial infarction.