Aim To investigate the clinical and pathological features of chronic kidney disease (CKD) 1-2 stage in chronic glomerulonephritis elderly patients with dyslipidemia, and to evaluate the effect of dyslipidemia on CKD. Methods A total of 111 elderly patients who underwent renal biopsy and were eligible for CKD1-2 with primary chronic glomerulonephritis from 2014 to 2017 were enrolled. According to the presence of hyperlipidemia, they were divided into hyperlipidemia group (HL Group) of 76 patients, and non-hyperlipidemia group (non-HL group) of 35 patients, the general data, clinical and pathological features of two groups were reviewed. Results (1) There were no significant differences in age, sex ratio, body mass index, prevalence of hypertension, pathological distribution, serum creatinine, and high-sensitivity C-reactive protein between the two groups. The levels of serum uric acid, 24 h urine protein, urinary transferrin, urinary albumin, urinary α1 microglobulin and urinary NAG were higher in the HL group than in the non-HL group, and serum albumin was lower than that in the non-HL group (P＜0.05). (2) The vascular injury scores of HL group was higher than that of non-HL group (P＜0.05), but the scores of glomerular sclerosis, proportion of crescent, mesangial hyperplasia and tubular injury were not statistically different. (3) By binary variable correlation analysis, 24 h urine protein and urinary transferrin were associated with serum cholesterol, triglyceride, low density lipoprotein, and high density lipoprotein; blood uric acid and urinary albumin were associated with serum cholesterol, triglycerides and low density lipoprotein; serum albumin and urinary NAG enzymes were associated with serum cholesterol, triglycerides, and low-density lipoprotein. Conclusion The CKD 1-2 elderly patients with chronic glomerulonephritis associated with dyslipidemia are more likely to get more severe urinary protein and tubule injury, and have higher risk of getting renal microvascular disease.