Obstructive sleep apnea hypopnea syndrome(OSAHS) is characterized by recurrent hypoxemia and hypercapnia at night. Recent fingdings show that OSAHS is closely associated with atherosclerosis cardiovascular disease(ASCVD)such as stroke,heart failure. And carotid intima-media thickness(CIMT)can predict ASCVD. So it is significant for preventing atherosclerosis(As) in OSAHS patients to study the relationship between IMT and OSAHS. This review summarized the recent research progress on the relationship between obstructive sleep apnea hypopnea syndrome and carotid intima-media thickness, including human epidemiological and related mechanism studies and related treatments. It can provide a background reference for interrupting the progress of As in OSAHS patients.