Advances in miR-34a:its roles and mechanisms in cardiovascular disease
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1.University of South China, Hengyang, Hunan 421001, China;2.Department of Cardiology, Guangdong Second Provincial General Hospital, University of South China, Guangzhou, Guangdong 510317, China;3.Department of Cardiology, the First People's Hospital of Chenzhou, University of South China, Chenzhou, Hunan 423000, China;4.School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong 510515, China)

Clc Number:

R541.4

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    Abstract:

    MicroRNA(miR)have been considered as the important regulators in both physiological and disease contexts, among which miR-34a has drawn great attention as its multiple functions in cardiovascular disease. It is reported that miR-34a is either upregulated or downregulated in atherosclerotic cardiovascular diseases, etc. This article reviews both the roles and mechanisms of miR-34a in cardiovascular diseases, aiming to provide new ideas for further researches on biomarkers and treatment target of cardiovascular disease.

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LI Xiaowei, FENG Shujun, ZHOU Fenghua, JIN Wen, ZHAO Yiqiao. Advances in miR-34a:its roles and mechanisms in cardiovascular disease[J]. Editorial Office of Chinese Journal of Arteriosclerosis,2019,27(7):624-628.

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History
  • Received:November 16,2018
  • Revised:January 24,2019
  • Online: June 04,2019
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