Recent progresses on related research of cells involved in vascular calcification

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Recent progresses on related research of cells involved in vascular calcification
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                        DONG QianqianDONG Qianqian
Department of Cardiology, Zhujiang Hospital, Southern Medical University & Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease & Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Guangzhou, Guangdong 510280, China
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YAN JianyunYAN Jianyun
Department of Cardiology, Zhujiang Hospital, Southern Medical University & Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease & Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Guangzhou, Guangdong 510280, China
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Affiliation:Department of Cardiology, Zhujiang Hospital, Southern Medical University & Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease & Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Guangzhou, Guangdong 510280, China)
Clc Number:R543
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Abstract:

Vascular calcification is an active cell- and gene-regulated process, involving imbalance between promoters and inhibitors of vascular calcification. It commonly occurs in patients with advanced atherosclerosis and is highly related with diabetes, chronic kidney diseases and aging. Osteogenic differentiation of vascular cells is the key contributor to vascular calcification, but the cell sources of vascular calcification remain unclear. It has been thought that the origins of cells regulating vascular calcification may include vascular smooth muscle cell, endothelial cell, pericyte, macrophage and progenitor cell. This review focuses on the regulatory role of cells in vascular calcification.

Key words:vascular calcification; vascular smooth muscle cell; endothelial cell; pericyte; macrophage; progenitor cell

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DONG Qianqian, YAN Jianyun. Recent progresses on related research of cells involved in vascular calcification[J]. Editorial Office of Chinese Journal of Arteriosclerosis,2018,26(11):1111-1115.

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Received:August 16,2018
Revised:September 26,2018
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Online: December 11,2018
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