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Research progress on the role of hydrogen sulfide in diabetic microvascular disease
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Affiliation:

1.Institute of Cardiovascular Disease Research & Key Laboratory for Atherosclerology of Hunan Province, ;2.Department of Pathophysiology, University of South China, Hengyang, Hunan 421001, China)

Clc Number:

R363

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    Abstract:

    As a newly discovered gas signal molecule after nitric oxide and carbon monoxide, hydrogen sulfide (H2S) has attracted wide attention from experts and scholars both at home and abroad, and has been carried out a lot of physiological and pathophysiological studies. Most scholars believe that H2S plays an important role in the development of diabetes and its microvascular disease. However, so far, the physiological and toxic effects of H2S in the human body are not completely clear, and most of the mechanisms of the H2S effect have not been fully elucidated. This paper reviews the role and mechanism of H2S in 3 common diabetic microangiopathy (diabetic retinopathy, diabetic neuropathy and diabetic nephropathy), in order to provide a new theoretical basis for the research and treatment of diabetic microangiopathy.

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ZENG Yun, HAO Ya-Meng, YUAN Hou-Qin, REN Zhong, JIANG Zhi-Sheng. Research progress on the role of hydrogen sulfide in diabetic microvascular disease[J]. Editorial Office of Chinese Journal of Arteriosclerosis,2018,26(4):414-418.

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History
  • Received:November 10,2017
  • Revised:December 27,2017
  • Online: May 04,2018
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