Phenotypic transformation of vascular smooth muscle cells in atherosclerosis

Home > Archive>Volume 26, Issue 1, 2018 >99-102

Phenotypic transformation of vascular smooth muscle cells in atherosclerosis
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                        SHU Liu-Fang1,2SHU Liu-Fang
Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China;The Third Department of Cardiology, Tianjin Peoples Hospital, Tianjin 300121, China
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JIANG Xi-Juan1JIANG Xi-Juan
Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
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YANG Lin1YANG Lin
Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
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WEI Li-Ping2WEI Li-Ping
The Third Department of Cardiology, Tianjin Peoples Hospital, Tianjin 300121, China
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QI Xin2QI Xin
The Third Department of Cardiology, Tianjin Peoples Hospital, Tianjin 300121, China
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Affiliation:1.Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China;2.The Third Department of Cardiology, Tianjin People's Hospital, Tianjin 300121, China)
Clc Number:R543.5
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Abstract:

In the process of atherosclerosis, media vascular smooth muscle cell phenotype transform, migrate and proliferate, enter the vascular intima, and participate in the formation of fibrous caps and neovascularization of atherosclerotic plaques. In this review, the current research progress on the role of vascular smooth muscle cell phenotype transformation to atherosclerosis is reviewed.

Key words:Atherosclerosis; Vascular smooth muscle cells; Phenotypic transformation; Cell proliferation; Cell apoptosis

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SHU Liu-Fang, JIANG Xi-Juan, YANG Lin, WEI Li-Ping, QI Xin. Phenotypic transformation of vascular smooth muscle cells in atherosclerosis[J]. Editorial Office of Chinese Journal of Arteriosclerosis,2018,26(1):99-102.

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Received:July 31,2017
Revised:October 11,2017
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Online: February 01,2018
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