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The research progress of mechanism of microRNAs which regulated by shear stress on atherosclerosis
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Affiliation:

1. Integrative Traditional Chinese and Western Medicine College, Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;2. Department of Pediatric, Affiliated Nanhua Hospital,University of South China, Hengyang, Hunan 421002,China;3. Medicine School, Hunan University of Chinese Medicine, Changsha, Hunan 410208, China)

Clc Number:

R543.5

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    Abstract:

    Atherosclerosis (As) is the main pathological basis of cardiovascular and cerebrovascular diseases, which seriously threatens human life and health. As occurs in abnormal shear stress sites, and microRNAs regulated by shear stress are called “shear stress sensitive microRNAs”. Shear stress-sensitive microRNAs are involved in many aspects of the pathogenesis of As. This review summarizes the recent advances in the mechanism of shear stress-sensitive microRNAs in the development and progression of As.

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LIU Jing, WANG Mei-Mei, HE Wen-Zhi, WEN Hong-Yan. The research progress of mechanism of microRNAs which regulated by shear stress on atherosclerosis[J]. Editorial Office of Chinese Journal of Arteriosclerosis,2017,25(12):1287-1290.

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History
  • Received:March 12,2017
  • Revised:October 31,2017
  • Online: December 28,2017
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