Aim To evaluate the diagnostic value of dual-source computed tomography in detecting coronary artery anomalies. Methods Clinical data of 5153 patients who underwent coronary CTA were retrospectively analyzed to determine the CT features of anomalous origin of coronary artery. Results In consecutive 5153 patients, 141 cases with anomalies origin were identified (2.74%), including 102 cases with trunk anomalous origin (1.98%), 39 cases of anomalous branches (0.76%). Conclusion Dual-source CT could accurately display the anomalous origin of the coronary and direction, provide a reference for clinical diagnosis and treatment.