Aim To investigate the change of ambulatory blood pressure (BP) for 7 days after admission and its impact on the prognosis for patients with acute hemorrhage stroke. Methods 141 patients with new onset acute hemorrhage stroke were enrolled. The 7-day/24-hour (24 h) ambulatory BP was monitored and the odd points of time of BP were collected per two hours. Related clinical data of patients were collected. The prognosis of patients was determined according to the 30-day Glasgow outcome scale (GOS) after admission, and the relationships of prognosis and ambulatory BP changes such as admission systolic BP (SBP) and diastolic BP (DBP), 7-day daytime/nighttime mean SBP and DBP, 7-day BP circadian rhythm (BPCR) changes etc, were analyzed. Results 7-day/24-h mean BP decreased gradually among patients with new onset acute hemorrhage stroke. The BP on the seventh day was significantly lower than that on the first day (P＜0.05). There was no significant difference in BPCR between two groups (P＞0.05). There were significant difference between two groups in 7-day/24-h BP, admission Glasgow coma scale (GCS), white blood cells (WBC), hospital days, midline shift, broken into the ventricle, history of hypertension, and admission SBP(P＜0.05). Multivariate logistic regression showed that admission high 24-h mean SBP, low admission GCS, high WBC, big amount of bleeding, basal ganglia hemorrhage were the risk factors for the poor prognosis of acute hemorrhage stroke (P＜0.05). Conclusion 7-day/24-h BP was higher in the poor prognosis group among patients with new onset acute hemorrhage stroke, and admission severe disease, big basal ganglia hemorrhage, high admission 24-h SBP were indicators for the severity of condition and poor prognosis. Monitoring and control of admission 24-h SBP and the amount of bleeding are beneficial for improving the prognosis of acute hemorrhage stroke.