The Role of Tissue Factor Pathway Inhibitor in Atherosclerosis
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Department of Cardiology, the First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, China)

Clc Number:

R363

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    Abstract:

    Tissue factor is closely related to the initiation and progression of atherosclerosis, and tissue factor pathway inhibitor(TFPI) is the main inhibitor of tissue factor-mediated coagulation. Ample experimental evidence indicates that TFPI has inhibitory effect on endothelial cell activity, the function of macrophages and smooth muscle cell proliferation and migration. This review focusses on the inhibitory effects of TFPI on the initiation and progression of atherosclerosis.

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LI Hui, MA Dan-Dan, FU Yu. The Role of Tissue Factor Pathway Inhibitor in Atherosclerosis[J]. Editorial Office of Chinese Journal of Arteriosclerosis,2016,24(3):306-310.

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History
  • Received:April 10,2015
  • Revised:June 08,2015
  • Online: April 15,2016
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