Aim To study the efficacy and safety of endovascular treatment for symptomatic subclavian artery occlusion or severe stenosis.Methods Endovascular treatment of symptomatic subclavian artery occlusion or severe stenosis was performed in 31 patients with the self-expanding stents.The efficacy and safety was analyzed.Results The self-expanding stents were technically successful in 31 patients with symptomatic subclavian artery occlusion or severe stenosis.Postoperative subclavian artery stenosis rate obviously improved,the subclavian artery steal blood syndrome and upper limb ischemia symptoms improved significantly,no complications appeared.Conclusion The self-expanding stent is minimally invasive and safe and effective in the treatment of symptomatic subclavian artery occlusion or severe stenosis.