Treatment delay is the main reason without effective treatment in the patients with acute coronary syndrome (ACS). It is urgent to solve this problem. Although the study of clinical pathway for ACS has been applied in July 2011. Using clinical pathway is not optimistic. Most of ACS visited grassroots medical institutions for the first time. However, there is no standard diagnosis and treatment, limited guide line and rescue process in the primary hospital. It is difficult to achieve reperfusion for the ACS. Therefore, the new regional cooperative treatment model may be the effective rescue of ACS.