The Influence of Renal Dysfunction on Diastolic Function and Systolic Function in Atherosclerotic Renal Artery Stenosis Patients
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    Abstract:

    Aim To investigate association of heart function with renal function in patients with atherosclerotic renal artery stenosis(ARAS)<70%. Methods Renal artery stenosis were <70% in 37 patiens with ARAS,they were divided into two groups based on endogenous creatinine clearance rate(CCr).CCr was detected by serum creatinine(SCr).Group A: 60 mL/min≤CCr<90 mL/min.GroupB: 30 mL/min≤CCr<60 mL/min.Left atrial diameter(LAD),left ventricular end-diastolic diameter(LVDd),interventricular septal thickness(IVST),left ventricular posterior wall thickness(IVPW),early and late wave of mitral valve flow(E/A),ejection fraction(EF),the inside diameter shortened fraction(FS) were determined using echocardiography. Results Compared with group A,indexes of cardia diastolic function and systolic function such as left ventricular ejection fraction(LVEF),EF,FS in group B were significantly decreased(P<0.05).Pearson correlation analysis indicated that CCr was positively correlated to the LVEF(r=0.324,P<0.05)and E/A(r =0.587,P<0.01). Conclusion Severity of diastolic dysfunction and systolic dysfunction correlate with the severity of renal dysfunction in ARAS patients.Renal dysfunction has a high clinical prediction in severity cardiovascular events in ARAS patients.

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HUANG Zhao-Hui, ZHAO Hong-Wen, WU Xiong-Fei, MAO Hua, JIANG Qing-An, and YANG Yong-Yao. The Influence of Renal Dysfunction on Diastolic Function and Systolic Function in Atherosclerotic Renal Artery Stenosis Patients[J]. Editorial Office of Chinese Journal of Arteriosclerosis,2011,19(12):1008-1010.

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  • Received:August 25,2011
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