The Relationship of JAK/STAT Signaling Pathway and Its Negative Regulators SOCS and Atherosclerosis

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The Relationship of JAK/STAT Signaling Pathway and Its Negative Regulators SOCS and Atherosclerosis
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                        HUANG Liang-Zhu,TIAN Ying,and LONG Shi-YinHUANG Liang-Zhu,TIAN Ying,and LONG Shi-Yin
Department of Biochemistry and Molecular Biology,University of South China,Hengyang 421001,China
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Abstract:

Atherosclerosis is multifactor disease,which is also the pathology basis of cardiovascular and cerebrovascular diseases.JAK/STAT signal pathway is strongly related to the occurrence,development,prevention and cure of atherosclerosis.The relationship between this signal pathway and its negative regulators SOCS and atherosclerosis is reviewed.

Key words:Atherosclerosis;JAK/STAT Signaling Pathway;Suppressor of Cytokine Signaling

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HUANG Liang-Zhu, TIAN Ying, and LONG Shi-Yin. The Relationship of JAK/STAT Signaling Pathway and Its Negative Regulators SOCS and Atherosclerosis[J]. Editorial Office of Chinese Journal of Arteriosclerosis,2010,18(8):665-668.

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Received:May 28,2010
Revised:August 02,2010
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