Caveolae is special invaginations in the plasma membrane,while caveolin is the marker protein of caveolae,which plays a role in the maintenance of caveolae structure and a variety of cellular processes,including endocytosis,cholesterol balance and signal transduction.Caveolin-1 is rich in many types of cells such as endothelial cells,smooth muscle cells,and plays an important role in angiogenesis and proliferation of smooth muscle cells.