Aim To explore the relationship between brachial-ankle pulse wave(baPWV)and flow-mediated vasodilation(FMD)in patients with coronary heart disease(CHD).Methods 98 patients with CHD and 33 control subjects were recruited in the study.baPWV velocity was measured non-invasively using VP 1000 automated ABI/PWV analyzer.Flow-mediated vasodilation(FMD)in the brachial artery was measured by high-resolution ultrasound.Results FMD was significantly reduced in CHD patients compared with that in control subjects(5.4%±2.5% vs 11.1±4.4%,p<0.01);and baPWV was increased in CHD group as compared to the control group(1745.3±215.2 cm/s vs 1495.3±202.3 cm/s,p<0.01).There was a significant correlation between baPWV and FMD in patients with CHD(r=-0.70,p<0.001).Conclusions There were increased baPWV and impaired endothelial function in patients with CHD.The correlation between flow-mediated vasodilation and brachial-ankle pulse wave velocity was high.