Aim To investigate the blood lipid status and dyslipdemia of 41 years old people group.Method Observe 4 219 cases of 41 years old people who come to take physical examination in hospital from 2004 to 2005.Blood lipid checking items include total cholesterol,low density lipoprotein cholesterol,high-density lipoprotein cholesterol and triglyceride.Result The blood lipid level of the group increases by age.Female's TC and LDLC are higher than male after 51,and female's HDLC is higher than male in all ages.High TC blood syndromes are more than high TG blood syndromes in each age groups.The rate of high TC of male in 41-60 age group is 29.5%,and that of female is 36.3%.41.0% for 60 age group of male and female 50.6%.The rate of high TG of male in 41-60 age group is 28.4%,and that of female is 10.9%.19.5% for 60 age group of male and female 15.5%.Conclusion The rate of dyslipdemia of above 41years old people in Huaihua city is high,it predicts that the risk of atherosclerotic cardiovascular disease increases.It is necessary to propaganda reasonable food structure arrangement and to prevent dyslipdemia.