Aim To study the value of non-high-density lipoprotein level in evaluation of coronary artery disease(CAD)in elderly patients.Methods 120 patients(75 cases and 45 controls)with selecting coronary angiography were enrolled in this case/control study.Fasting venous samples were ascertainted before coronary angiography and total cholesterol,triglycerid,high density lipoprotein cholesterol,low density lipoprotein cholesterol and non high-density lipoprotein cholesterol(n-HDLC)were measured respectively.The result of lipid analysis in the tow groups were studied by SPSS11.5 software.Results serum level of n-HDLC in the positive angiography group had significant higher than in the negative group 2.99±1.08 mmol/L,single-vesell group 3.41±0.59 mmol/L;double-vesellgroup 3.70±1.30 mmol/L;three-vesell group 3.77±1.10 mmol/L,respectively(p<0.001).The serum n-HDLC level increased with the severity of coronary stenosis,and had a grade assiociation with coronary stenosis scores(r=0.326,p<0.001).There was no significant difference in serum triglycerid and high-density lipoprotein level between the two groups(p>0.05).Conclusion non-high-density lipoprotein is a low-cost and effective coronary artery disease risk assessment for elderly patients.