Aim To study the association of TaqIB polymorphism of the cholesteryl ester transport protein(CETP) gene in Chinese population via meta analysis. Methods Case-control studies published before 31 Dec.2005 about the association of CETP gene TaqIB polymorphism and coronary artery disease in Chinese population were searched in three digital databases including CBMdisc,CHKD and Medline. All the literatures were evaluated and abstracted based on the defined selection criteria by two independent investigators.Publication bias was tested by funnel plot and the odd ratios of all studies were combined dependent on the result of heterogeneity test among the individual studies.The software Review Manager (Version 4.2) was used for meta analysis. Results Seven studies containing 1 161 patients with coronary artery disease and 1 149 control subjects were analyzed. There was no publication bias in 7 reviewed studies,heterogeneity test of reviewed studies showed that there was no significant statistic differences(χ2=3.53,P=0.74) among the OR of individual studies. The summarized odds ratio of coronary artery disease for B1B1 genotype versus B1B₂ and B₂B₂ genotypes across all 7 studies was 1.34(95% CI: 1.12～1.60,P=0.002). Conclusion In Chinese Han nationality,the TaqIB polymorphism in CETP gene is associated with susceptibility of coronary artery disease and the allele B1 might be a genetic risk factor for coronary artery disease.