Aim To identify, clone and sequence Chinese ma ture Phospholipicl Transfer Protein (PLTP) peptide gene. Methods Total RNA was extracted from Chinese fetal liver tissue, cDNA fragment encoding human PLTP was amplified by RT PCR using specific primers, and then was cloned into pGEM T vector. Inserted PLTP gene was sequenced by ABI 377 DNA Sequenc er. Results Chinese PLTP gene was successfully cloned. Conclusion Analytical result indicates it is 1 428 b ase pairs in length and has 100% nucleotide homology with that reported previous ly.