Aim To study the association between C-reactive protein(CPR) and acute coronary artery syndrome. Methods CRP concentration were examined in 46 patients with acute myocardial infarction, 40 patients with unstable angina and 42 patients with stable angina. The effect of different dosages of aspirin on CRP concentration of acute myocardial infarction patients. Results CRP concentration in patients with acute myocardial infarction and unstable angina were significantly higher than that of patients with stable angina (P<0.001). CRP concentration in patients with acute myocardial infarction could be reduced with 300 mg/d dosage of aspirin (P<0.05). Conclusion CRP concentration as a prognostic marker may be useful in the evaluation of acute coronary artery syndrome