CT混合征、岛征联合渗漏征预测脑出血早期血肿扩大的临床价值研究
作者:
作者单位:

(1.宁波市泌尿肾病医院放射科,;2.浙江大学明州医院药剂科,浙江省宁波市 315100)

作者简介:

枟涛,硕士,研究方向为心脑血管疾病诊断,E-mail为yztano@163.com。通信作者白骏,硕士,副主任医师,研究方向为心脑血管疾病诊断,E-mail为344490043@qq.com。

基金项目:

浙江省医药卫生科技计划面上项目(2020KY896)


Clinical value of CT blend sign and island sign combined with leakage sign in predicting hematoma enlargement in the early stage of intracerebral hemorrhage
Author:
Affiliation:

1.Department of Radiology, Ningbo Urinary and Renal Diseases Hospital, ;2.Department of Pharmacy, Zhejiang University Mingzhou Hospital, Ningbo, Zhejiang 315100, China)

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    摘要:

    目的 探讨颅脑CT平扫混合征、岛征联合CT增强渗漏征对脑出血(ICH)早期血肿扩大的预测价值。方法 6 h内ICH基线CT平扫血肿内存在混合征、岛征血肿扩大危险因素的患者,行CT增强动脉期及延迟3 min扫描,根据是否存在渗漏征分为渗漏征阳性组和渗漏征阴性组。收集临床资料进行组间比较;分析与血肿扩大的关系;对早期血肿扩大影响因素进行Logistic回归分析;评估对ICH早期血肿扩大的预测价值。结果 渗漏征阳性组入院GCS评分显著低于渗漏征阴性组,差异有统计学意义(P<0.05)。渗漏征阳性组复诊血肿体积显著大于初诊血肿体积。Logistic回归分析显示混合征、岛征及渗漏征均为早期血肿扩大的主要危险因素。混合征、岛征联合渗漏征预测急性ICH早期血肿扩大的灵敏度为94.29%,特异度为97.22%。结论 CT平扫混合征、岛征联合CT增强渗漏征对ICH早期血肿扩大具有较高预测价值。

    Abstract:

    Aim To explore the predictive value of CT blend sign and island sign combined with CT enhanced leakage sign in the early hematoma enlargement in patients with intracerebral hemorrhage(ICH). Methods Patients with blend sign and island sign hematoma enlargement risk factors in ICH baseline CT scan within 6 hours were scanned by CT enhanced arterial phase and delayed 3 min scan. The patients were divided into two groups according to the presence of leakage sign:leakage sign positive group and leakage sign negative group. The clinical data were collected and compared between groups, and the relationship with hematoma enlargement was analyzed. In addition, the influencing factors of early hematoma enlargement were analyzed by Logistic regression analysis, and the predictive value of early hematoma enlargement in ICH was evaluated.Results The admission GCS score of the group with positive leakage sign was significantly lower than that of the group with negative leakage sign(P<0.05). The volume of hematoma in the group with positive leakage sign was significantly larger than that in the group with positive leakage sign. Logistic regression analysis showed that blend sign, island sign and leakage sign were the main risk factors for early hematoma enlargement. The sensitivity and specificity of blend sign and island sign combined with leakage sign in predicting early hematoma enlargement in acute ICH were 94.29% and 97.22%, respectively. Conclusion CT plain scan blend sign and island sign combined with CT enhanced leakage sign have high predictive value for early hematoma enlargement in ICH.

    参考文献
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枟涛,陈俊波,顾钱峰,夏文评,王超,白骏. CT混合征、岛征联合渗漏征预测脑出血早期血肿扩大的临床价值研究[J].中国动脉硬化杂志,2021,29(6):534~538.

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  • 收稿日期:2020-02-22
  • 最后修改日期:2020-06-12
  • 在线发布日期: 2021-06-11