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王梦琦,余瑾,李先法,朱彩凤.高BMI与IgA肾病相关性的研究进展[J].中国动脉硬化杂志,2019,(3):273~276
高BMI与IgA肾病相关性的研究进展
Andvances in studies on high BMI index and IgA-nephropathy
投稿时间:2018-07-12  修订日期:2018-12-19
DOI:
中文关键词:  IgA  肾病  体质指数  肥胖
英文关键词:IgA nephropathy  body mass index  obesity
基金项目:浙江省中医药科技计划项目(2016ZA142);杭州市科技发展计划项目(20160533B59);浙江省朱彩凤名老中医传承工作室研究项目(GZS2017013)
作者单位E-mail
王梦琦 浙江中医药大学附属广兴医院肾内科, 浙江省杭州市 310007 e-mail为13738052864@163.com,e-mail为478234460@qq.com 
余瑾 杭州市中医院肾内科, 浙江省杭州市310007 e-mail为13738052864@163.com,e-mail为478234460@qq.com 
李先法 杭州市中医院肾内科, 浙江省杭州市310007  
朱彩凤 杭州市中医院肾内科, 浙江省杭州市310007  
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中文摘要:
      免疫球蛋白A肾病(IgAN)是中国最常见的原发性肾小球疾病,可发于任何年龄,呈慢性进行性进展,现有资料显示,约20%~40% IgAN患者10~20年后发展至终末期肾脏病(ESRD)。IgAN进展因素繁多,除公认的免疫因素以外,近年报道体质指数(BMI)、胰岛素抵抗(IR)及高尿酸血症等多种代谢性因素亦和IgAN进展相关。而高BMI患者合并肾脏疾病,也并非均为肥胖相关性肾病,IgAN并不少见。该文就高BMI与IgAN相关性作一综述。
英文摘要:
      IgAN is the most common primary glomerular disease in China. It can occur at any age and progress chronically. Current data show that about 20%~40% of patients develop to end-stage kidney in 10~20 years. There are many factors contributing to the progress of IgAN. In addition to the recognized immune factors, many metabolic factors such as body mass index, insulin resistance and hyperuricemia have been reported in recent years, which are also related to the progress of IgAN. IgAN is not uncommon in patients with high BMI and kidney diseases, which are not all obesity-related nephropathy. This paper reviews the correlation between high BMI index and IgAN.
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