氢氧混合气对健康人皮肤血流灌注的影响

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氢氧混合气对健康人皮肤血流灌注的影响
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作者单位:(1.山东省高校动脉粥样硬化重点实验室 泰山医学院动脉粥样硬化研究所 泰山氢生物医学研究院;2.泰山医学院附属医院,山东省泰安市 271000)
作者简介:于杨,博士,副教授,主要研究方向为动脉粥样硬化与脂质代谢、氢分子生物医学,E-mail为thereismywill@hotmail.com。赵云来为共同第一作者。
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基金项目:国家自然科学基金项目(81770855,81670422)；山东省泰山学者专项基金项目(ts201511057,tsqn20161045)

The effects of hydrogen-oxygen mixed gas on skin blood flow in healthy adults

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1.Key Laboratory of Atherosclerosis in Universities of Shandong ＆ Institute of Atherosclerosis, Taishan Medical University ＆ Taishan Institute for Hydrogen Biomedical Research;2.Affiliated Hospital of Taishan Medical University)

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目的测试健康人吸入高浓度氢氧混合气对皮肤循环血流量的影响。方法应用MoorFLPI-2激光散斑血流实时成像系统,检测12名健康成人志愿者吸入高浓度氢氧混合气(66.7%氢+33.3%氧)前后面部和手部皮肤循环血流量。结果吸入氢氧混合气半小时后,面部皮肤血流量较吸气前增加9.7%(P＜0.05),手背部皮肤血流量较吸气前增加27.1%(P＜0.01),对指尖等部位血流量增加作用尤其明显。结论短时吸入氢氧混合气能显著增加健康人面部和手部皮肤血流灌注量。

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Aim To investigate the effects of high concentration hydrogen-oxygen mixed gas (HCHOG) on skin blood flow. Methods Using MoorFLPI-2 Laser Speckle blood stream real-time imaging system, the blood flow amount in facial and hand skin before and after the inhalation of HCHOG (66.7% hydrogen gas + 33.3% oxygen gas) were examined in 12 healthy adult volunteers, respectively. Results After 30 minutes of HCHOG inhalation, the facial skin blood flow (FSBF) was increased by 9.7% (P＜0.05) compared with the FSBF before HCHOG inhalation. The dorsum of hand skin blood flow (DHSBF) was increased significantly by 27.1% (P＜0.01) compared with the DHSBF before HCHOG inhalation. Conclusion A short-time inhalation of HCHOG notably enhanced the FSBF and DHSBF in healthy adults, respectively.

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于杨,赵云来,宋国华,秦树存.氢氧混合气对健康人皮肤血流灌注的影响[J].中国动脉硬化杂志,2018,26(6):557~560.

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收稿日期:2018-04-19
最后修改日期:2018-05-30
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在线发布日期: 2018-07-10

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