Aim To explore changes of serum resistin,serum high-sensitivity cardiac troponin T （hs-cTnT） and their correlation with left heart parameters in maintenance hemodialysis （MHD） patients. Methods 60 MHD patients,45 chronic renal failure paitients with non-hemodialysis （non-HD） and 40 healthy controls were selected. Resistin,hs-cTnT and C-reactive protein （CRP） were determined. Left heart function parameters were measured. Results Resistin,hs-cTnT and CRP were significantly higher in MHD patients and non-HD patients compared to healthy controls （all P<0.01）. Left ventricular end-diastolic dimension （LVEDD）,left ventricular mass index （LVMI） and left atrial diameter （LAD） were significantly higher in MHD patients compared to healthy controls （all P<0.01）. Left ventricular ejection fraction （LVEF）,left ventricular fractional shortening （LVFS） and E/A were significantly lower in MHD patients compared to healthy controls （all P<0.01）. LVEDD,LVMI and LAD were significantly higher in non-HD patients compared to healthy controls （all P<0.01）. LVEF （P<0.05）,LVFS （P<0.05） and E/A （P<0.01） were significantly lower in non-HD patients compared to healthy controls. Resistin,hs-cTnT,CRP,LVEDD and LVMI were significantly higher in MHD patients compared to non-HD patients （all P<0.01）. Resistin was positively related with hs-cTnT,CRP （all P<0.05） in MHD patients. Resistin,hs-cTnT were positively related with LVEDD,LVMI （all P<0.05）,and negatively related with LVEF,LVFS （all P<0.05） in MHD patients. Conclusions Resistin,hs-cTnT and CRP were increasing significantly in MHD patients and non-HD patients. There were correlation of hs-cTnT with left heart function parameters in MHD patients. The higher level of resistin in MHD patients may relate to their microinflammatory status and cardiovascular diseases.