Aim First, to investigate the influence of the injectable vinpocetine to QT dispersion in elderly patients with coronary heart disease, then, to assess the association between QT dispersion and coronary heart disease risk factors before treatment in elderly patients. Methods 150 cases elderly patients with coronary heart disease were randomly divided into 3 groups, including control group （fifty cases）, 30 mg group （fifty cases） and 50 mg group （fifty cases）. The control group was given conventional western medicine treatment,the treatment group was given the injectable vinpocetine （divided into 30 mg, 50 mg） on the basis of the conventional western medicine treatment, 1 time/day, 9 days as one period. The changes of QT dispersion were observed in three groups before and after the treatment,and the correlation was analysed between QT dispersion and age, gender, heart rate, body mass index, systolic blood pressure, diastolic blood pressure, pulse pressure, pulse pressure index, fasting blood sugar, total cholesterol, triglyceride, low density lipoprotein cholesterol, high density lipoprotein cholesterol before treatment. Results ①QT dispersion in comparison of the three groups before treatment had no significant difference （P>0.05） After treatment, the comparisons between 50 mg group and control group, 30 mg group respectively were significantly different（P﹤0.01 and 0.05）The comparisons between before and after treatment of 30 mg group and 50 mg group were significantly different（P﹤0.05 and 0.01）. ②Single factor correlation analysis showed, a positive significant correlation was found between QT dispersion and systolic blood pressure （r0.758, P<0.01）, pulse pressure （r0.737, P<0.01）, pulse pressure index （r0.630, P<0.01）, triglyceride（r0.251, P<0.01）, fasting blood sugar（r0.172, P<0.05） A negative significant correlation was observed between QT dispersion and diastolic blood pressure（r－0.192, P<0.05）. Multiple linear regression analysis showed an independent association between QT dispersion and pulse pressure, pulse pressure index, triglyceride.Conclusions Vinpocetine can shorten QT dispersion in elderly patients with coronary heart disease, and which was more significant in 50 mg group than 30 mg group. QT dispersion were associated with coronary heart disease risk factors in elderly patients. By testing pulse pressure, pulse pressure index, triglyceride levels in elderly patients with coronary heart disease can provide certain help to evaluate QT dispersion.