AimTo observe the impact of Shuxuening on the clinical effects and quality of life in old patients with ischemic stoke.Methods212 old patients with ischemic stroke were randomly divided into study group and control group.The control group was treated with conventional therapy; the study group was treated with Shuxuening additionally.All were treated for 2 weeks.The nerve function deficit score was evaluated, SS-QOL table was used to evaluate the quality of life in patients, the level of endothelin-1 (ET-1) and calcitonin gene related peptide(CGRP) were recorded.ResultsAfter treatment, the clinical efficiency were 86.8% in study group and 76.5% in control one(p<0.05); for the study group, the score of SS-QOL and CGRP increased greatly,ET-1 decreased greatly, and there were significant difference between the two groups (p<0.05 or p<0.01).ConclusionCombined with conventional therap, Shuxuening could improve the nerve function deficit score and quality of life in old patients with ischemic stoke.