AimTo evaluate the efficacy and safty of thrombus aspiration without additional ballooning or stenting to treat patients with ST-elevation myocardial infarction.MethodsWe report the angiographic and clinical outcome of a series of selected ST-elevation myocardial infarction patients undergoing mechanical reperfusion by thrombus aspiration with or without additional ballooning or stenting.Thoracalgia and elevated ST segment resolution rate 2 hours after intervention, peak values of creatine kinase (CK) and creatine kinase-MB (CK-MB), left ventricular ejection fraction (LVEF) in 5-7 days, stenting and secondary outcomes 1 month after intervention were compared.ResultsThe rate of stenting in group A is significantly lower than group B; other index were not significantly different from these two groups.ConclusionIn selected patients with ST-elevation myocardial infarction undergoing mechanical reperfusion, thrombus aspiration without additional ballooning or stenting may be successfully performed.