AimTo discuss clinical efficacy and safety of symptomatic middle cerebral artery (MCA) stenosis Wingspan stent placement.MethodsThe retrospective analysis includes 23 cases of symptomatic MCA acute ischemia and medical treatment-failed MCA M1 stenosis receiving self expandable Wingspan stent and 8 clinical cases of MCA M1 stenosis acute ischemia which enjoy stent treatment indications but receive medical treatment instead of stent treatment for economic reasons.Stent group receives Gateway sacculus pre-expansion and then is implanted with self expandable Wingspan stent.Medicine group receives edaravone injection and salvia miltiorrhiza needle and effect evaluation 7, 14 and 21 days after the operation and group’s clinical curative effect is then analyzed.ResultsThere is significant difference between the two groups 14 and 21 days after treatment in improvement of neural function and daily life activities.ConclusionsWingspan self expandable stent placement on symptomatic M1 stenosis is feasible, safe and effective.Recent follow-up visits have confirmed its curative effects in effectively improving neurologic impairment resulting from acute cerebral infarction and daily life ability.But it is a high-technical wounded treatment.Therefore indications must be strictly treated to prevent abuse for sake of security.