AimTo investigate the association between the connexin37 (Cx37) gene C1019T polymorphisms and the risk of Kawasaki disease (KD) and that complicated with coronary artery lesion (CAL).MethodsA total of 45 patients with KD and 60 healthy controls were genotyped by using polymerase chain reaction-restriction fragment length polymorphism and agarose gel electrophoresis for the C1019T polymorphism in Cx37 gene.ResultsFor C1019T polymorphism in Cx37 gene, there were no significant differences between KD patients and the controls in genotype frequencies of CC, TC and TT and allele frequencies of C and T (χ²=1.411 and 0.003, both p>0.05); there were no significant differences between KD patients with CAL and that without CAL in genotype and allele frequencies (χ²=0.633 and 0.438, both p>0.05).ConclusionNo association was found between C1019T polymorphism in Cx37 gene and the risk of KD or its complication of CAL in this study.