颈动脉血管弹性与冠状动脉狭窄的相关性
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The Correlation Analysis of Carotid Artery Elasticity with Coronary Stenosis
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    目的探讨颈动脉血管弹性与冠状动脉狭窄的相关性。方法对100例入选者行冠状动脉血管造影,同期内(间隔<15天)采用颈动脉E-tracking技术检测颈动脉血管弹性。根据造影结果将冠心病组分为冠状动脉单支病变组、双支病变组(左主干病变包括在内)和多支病变组。比较各组间颈动脉血管弹性变化与冠状动脉狭窄的相关性。结果冠心病组与对照组比较颈动脉血管弹性指标僵硬度参数β、压力应变弹性系数Ep及动脉顺应性AC降低,冠状动脉多支病变组颈动脉血管弹性指标较其他组降低;冠状动脉单支、双支病变组与对照组比较差异无统计学意义;单支、双支病变组间弹性比较无统计学意义。冠状动脉发生多支病变时其外周颈动脉血管弹性有明显的降低。结论用E-tracking技术检测到颈动脉血管弹性的指标僵硬度参数β、压力应变弹性系数、动脉顺应性的异常与冠状动脉病变关系密切,可作为预测冠心病危险的有价值指标。

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    Aim To investigate the correlativity of carotid artery elasticity and coronary arterial stenosis. Methods 100 subjects who underwent coronary angiography(CAG) were subject to a contemporary examination of ET examination(<15 days).According to the results of CAG,the subjects were divided into four groups,normal,single-branch lesion,two-branch lesion(including left aim branch) and multi-branch lesion.The parameters of carotid elasticity,stiffness parameter β(β),pressure strain elastic modulus(Ep),arterial compliance(AC),were measured by ET technique,and the correlativity of carotid artery elasticity and coronary arterial stenosis was studied. Results The parameters of the carotid elasticity,β,Ep and AC,changed with the development of the coronary heart disease(CHD).Compared with normal subjects,elasticity of the carotid arteries was even worse in CHD patients,especially in multi-branch lesion group.There was no statistical difference in carotid elasticity among normal group,one-branch lesion group and two-branch lesion group.The carotid elasticity decreased more in multi-vessel lesion group than other groups. Conclusions There is a close correlation between carotid elasticity and coronary stenosis.The parameters of carotid elasticity measured by ET(β,Ep and AC) can be used to predict the degree of the coronary stenosis,suggesting their potential roles in distinguishing different risk levels for CHD.

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王丽辉,葛永祥,王晓云.颈动脉血管弹性与冠状动脉狭窄的相关性[J].中国动脉硬化杂志,2011,19(12):1033~1036.

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  • 收稿日期:2010-08-03
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